While a causal relationship exists between oxidative phenotype and protein turnover, the disruption of oxidative metabolism
can negatively impact both basal and induced protein synthesis in muscle.
Lopaschuk, "Targeting mitochondrial oxidative metabolism
as an approach to treat heart failure," Biochimica et Biophysica Acta (BBA)--Molecular Cell Research, vol.
We have hypothesized that the frequent association of dysautonomia with recognizable disease entities is related to defective oxidative metabolism
that affects the limbic system control mechanisms first because it has a well known high oxygen requirement.
Various inflammatory stimuli such as excessive ROS/RNS produced in the process of oxidative metabolism
and some natural or artificial chemicals have been reported to initiate the inflammatory process resulting in synthesis and secretion of proinflammatory cytokines.
Some of the monoester is converted into other chemical species by oxidative metabolism
in bodily tissues, and some of it is excreted in the urine as acyl glucuronides.
The high levels of circulating lipids increase the lipoperoxidation of lipids, which diminish the antioxidant systems such as superoxide dismutase and catalase and cause, as a consequence, the high levels of oxidative metabolism
which affects cell structure, causing neuronal damage.
Therefore, recent proposals tend to prevent, rather than counteract, ROS production, particularly at the mitochondrial level, during oxidative metabolism
(the mitochondrial free radical theory of aging) .
(2007) Tricarboxylic acid cycle intermediate pool size: functional importance for oxidative metabolism
in exercising human skeletal muscle.
A superfamily of enzymes called cytochromes P450 (CYPs) play essential roles in controlling herbicide selectivity, as they can detoxify a wide range of chemistries through catalysing their oxidative metabolism
, thereby allowing the compounds to be further modified and safely stored.
Mitochondrial oxidative metabolism
increases under certain stress conditions and such energy demands lead to a clinical manifestation detectable in the different gland types.
Therefore, NOS activity and NO production are important indicators of oxidative metabolism
Allesio et al  showed that increased locomotory activity is correlated with a more efficient mechanism for controlling muscle oxidative metabolism
and free radical production.