The peroxidation of leukocytes index ratio (PLIR) measures the resistance of leukocytes to exogenous oxidative stress and their functional capacity of oxidative burst
upon activation .
The results obtained in this study highlight a short-term oxidative DNA damage induced by CABG procedure in CAD patients and a complete recovery of this oxidative burst
six months after the procedure.
In contrast, CD137, a costimulatory immune checkpoint molecule, could reduce typical macrophage characteristics such as phagocytosis, oxidative burst
, and CD14 expression, which could induce the differentiation of monocytes to dendritic cells (DC) and DC maturation and reduce ROS generation .
Additionally, oxidative burst
is also required in the clearance of apoptotic cells by alternatively activated macrophages during wound healing process .
The reduced muscle damage response in NAC may be further explained by previous observations of attenuated eccentric exercise-induced muscle injury following neutrophil and macrophage depletion suggesting that neutrophil's/macrophages' oxidative burst
maybe responsible for part of muscle's injury during early recovery [32, 61].
In this context, although oxidative stress is involved in metabolic syndrome, decreases in oxidative burst
of neutrophils occurred in some conditions, such as hypercholesterolemia  and non-insulin-dependent diabetes mellitus (NIDDM) .
In addition, they focus on mitochondria-targeted MitoQ and SkQ antioxidants and propose astaxanthin, a carotenoid, for acute inflammatory conditions characterized by pathologically increased oxidative burst
, for example, avian influenza with acute respiratory distress syndrome and ischemia-reperfusion.
Nabinger et al., "Protein-tyrosine phosphatase Shp2 positively regulates macrophage oxidative burst
," Journal of Biological Chemistry, vol.
The antigen receptors are themselves OS-generating enzymes, contributing further to enhancing the cellular "oxidative burst
" against exogenous pathogens as well as neighbouring cells , causing autoinflammatory and/or allergic diseases [17, 38].
Thaler, "Oxidative burst
of neutrophils in patients with rheumatoid arthritis: influence of various cytokines and medication," Clinical and Experimental Rheumatology, vol.
The massive production of antimicrobial and tumoricidal ROS in an inflammatory environment is called "oxidative burst
" and plays an important role as the first line of defense against environmental pathogens.
In the response to various stimuli, the cells produce a large variety of ROS ([O.sub.2.sup.*-], [H.sub.2][O.sub.2], H[O.sup.*], hypochlorous acid (HOCl), and N-chloroamines (R-NHCl)) during a process called the oxidative burst
in order to kill pathogens.