oxandrolone

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steroid

 [ster´oid]
any of a group of lipids with a complex molecule containing carbon atoms in four interlocking rings forming a hydrogenated cyclopentophenanthrene-ring system; three of the rings contain six carbon atoms each and the fourth contains five. Steroids are important in body chemistry and include steroid hormones such as the gonadal or sex steroids, corticosteroids, glucocorticoids, and mineralocorticoids; vitamins of the D group; and the sterols, including cholesterol, the main building block of the steroid hormones in the body. The cardiac glycosides, a group of compounds derived from certain plants, are partly steroids.
anabolic steroid any of a group of synthetic derivatives of testosterone having pronounced anabolic properties and relatively weak androgenic properties; they are used clinically mainly to promote growth and repair of body tissues in diseases or states promoting catabolism or tissue wasting.
gonadal steroid (sex steroid) a steroid hormone produced by a gonad, such as an androgen, estrogen, or progestational agent.

oxandrolone

/ox·an·dro·lone/ (ok-san´dro-lōn) an androgenic and anabolic steroid that is used in the treatment of catabolic or tissue-wasting diseases or states.

oxandrolone

[oksan′drəlōn]
an androgen.
indications It is prescribed in the treatment of bone pain accompanying osteoporosis and for the stimulation of weight gain after extensive surgery or trauma or when a pathophysiological reason exists for failure to maintain normal weight.
contraindications Cancer of the male breast or prostate, liver disease, pregnancy or suspected pregnancy, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse reactions are hirsutism, acne, liver toxicity, electrolyte imbalances, and various endocrine effects in some patients.

oxandrolone

Oxandrin® Endocrinology An anabolic steroid used to reverse involuntary weight loss and depletion of cell mass, in Pts with AIDS, trauma, chronic infection, major burns or surgery, and other debilitating conditions Adverse effects Hepatotoxicity, cholestasis, liver cell necrosis, peliosis hepatis, hirsutism, gynecomastia, acne, male pattern baldness in ♀. See Anabolic steroid.

oxandrolone (oksan´drəlōn´),

n brand name: Oxandrin;
drug class: androgenic anabolic steroid (Controlled Substance Schedule III);
action: reverses catabolic tissue processes; promotes buildup of protein; increases erythropoietin production;
uses: treating catabolic or tissue-wasting processes, such as extensive surgery, burns, infection, or trauma; HIV wasting syndrome; Turner's syndrome.
References in periodicals archive ?
Oxandrin (oxandrolone tablets, USP) is indicated as adjunctive therapy to promote weight gain after weight loss following extensive surgery, chronic infections, or severe trauma, and in some patients who without definite pathophysiologic reasons fail to gain or to maintain normal weight, to offset the protein catabolism associated with prolonged administration of corticosteroids, and for the relief of the bone pain frequently accompanying osteoporosis.
Anadrol, Oxandrin, and Durabolin are anabolic steroids--artificial versions of the hormone testosterone.
She noted that some doctors make the mistake of just giving Oxandrin (oxandrolone, an anabolic steroid, which helps build muscle mass), when the real problem is that the patient will not eat.
Concurrent use of Oxandrin (oxandrolone) and warfarin can cause serious bleeding, according to Savient Pharmaceuticals Inc.
Net product sales of Oxandrin for the fourth quarter of 2007 were $0.
2 million from our authorized generic of Oxandrin, oxandrolone.
8 million primarily due to generic competition in 2007 for Oxandrin.
In 2007, the revenues from Oxandrin include both the sales of branded Oxandrin and the revenues from the distribution agreement for generic oxandrolone through Watson Pharmaceuticals.
4 percent for those treated with Oxandrin and a nutritional supplement, compared with 20.
Clement continued, "The approval of Oxandrin([R]) generics in December was an eventuality we anticipated and planned for, and while it will result in a significant reduction in our future revenue and cash flow, it will be offset somewhat by our partnership with Watson Pharmaceuticals on the sale and distribution of an authorized generic version of Oxandrin.
Gynex has two Treatment INDs for Oxandrin allowing it to recover its basic costs while clinical testing and FDA review are underway.