Metabolism A proprietary urine test for measuring bone loss, quantifying cross-linked N-telopeptides–NTx, which are degradation products of bone resorption and are unique biochemical markers specific for the type I collagen–found in bone. See Hormone replacement therapy, N-telopeptides, Osteoporosis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
NTx, a marker of bone resorption, was measured in urine by competitive-inhibition enzyme-linked solid-phase immunosorbent assay (Osteomark; NHANES 1999-2001) or Vitros Eci competitive assay (NHANES 2002).
A group of researchers compared the Pyrilinks-D test to other bone resorption tests like Osteomark and CrossLaps.
Serum NTX was measured by ELISA (Osteomark NTX serum; Ostex International) (18,19) with an intraassay CV of 4.6%.
A urine test developed by OSTEOMARK can determine whether a woman's body is losing bone density.
NTx was measured by ELISA (Osteomark; Ostex International Inc.) in a microtiter plate format.
The NTx test is an enzyme-linked immunosorbent assay of urinary cross-linked N-telopeptides of type 1 collagen, which are specific to bone and are stable in urine (OSTEOMARK, Ostex International, Seattle, WA, USA).
sALP was determined by the Tandem-MP Ostase Immunoenzymetric Assay (Beckman Coulter) (10) and NTx by the Osteomark NTx Assay (Ostex International) (11).
We thawed and analyzed aliquots of urine samples for NTx by a commercially available competitive-inhibition enzyme-linked immunosorbent assay (22) (Osteomark; Ostex International, Seattle, WA).
P1NP was measured by radioimmunoassay (Procollagen Intact PIMP; Orion Diagnostica) (5,6), and NTx was measured with a competitive-inhibition ELISA (Osteomark; Ostex) (7-9).
NTX and CTX were measured Respectively with the NTX ELISA immunoassay (Osteomark, Ostex Inc.) and with the CrossLaps ELISA immunoassay (CTX) (Osteometer A/S[R]).