Several studies have attempted to treat osteonecrosis by transplanting exogenous stem cells (MSCs) either systemically or locally, or biphasic calcium phosphate (BCP) ceramic scaffolds seeded with MSCs on inducing osteointegration
and new bone formation.
Unwanted material contamination on implant surfaces affects osteointegration
, stability and success.
In addition, they claimed that unresorbed granules within the newly formed bone were undesirable because it interfered with new bone growth and compromised the properties of the regenerated tissue, especially the osteointegration
Orthopedic polymers also offer the potential to be enhanced with additives to facilitate osteogenesis and/or osteointegration
In addition, the natural surface roughness of powder bed printing has been found to accelerate osteointegration
Osteoporosis will cause mandible resorption, which in turn cause the failure of osteointegration
between the implant and the jaw bone .
of solvent preserved bone transplants in an animal model.
In fact, the surface analysis of sol-gel materials and coatings has shown the presence of hydroxyl groups that can promote the nucleation of calcium and phosphate and, therefore, the osteointegration
when those materials are implanted .
A preliminary study on the enhancement of the osteointegration
of a novel synthetic hydroxyapatite scaffold in vivo.
In both reports, osteointegration
was successful with satisfactory functional results.
Alcohol detoxification is efficient, because it enhances osteogenesis, osteointegration
, calcemia and bone mechanical resistance (Horvath et al.
Second, this model only evaluated initial fixation and does not simulate the impact of any osseous integration; it is unknown whether implant osteointegration
in the clinical situation may mitigate early fixation vulnerabilities.