giant cell tumor of bone

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gi·ant cell tu·mor of bone

a soft, reddish-brown, sometimes malignant, osteolytic tumor composed of multinucleated giant cells and ovoid or spindle-shaped cells, occurring most frequently in an end of a long tubular bone of young adults.
Farlex Partner Medical Dictionary © Farlex 2012

giant cell tumor of bone

A lesion that comprises 5% of all osseous tumors, which is most common in the weight-bearing epiphysis of ♀ > age 20, which affects the distal femur, proximal tibia, distal radius; 60% recur with curettage; 10% metastasize, an event far more common in deep–to the fascial planes–tumors DiffDx A GCT-like histopathologic lesion may be seen in the brown tumor of hyperparathyroidism, chondroblastoma, giant cell reparative granuloma, benign and malignant fibrous histiocytoma, nonossifying and chondromyxoid fibroma, unicameral bone cyst, aneurysmal bone cyst, fibrous dysplasia, osteoblastoma, osteosarcoma, osteoid osteoma, eosinophilic granuloma.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

gi·ant cell tu·mor of bone

(jī'ănt sel tū'mŏr bōn)
A soft, reddish-brown, sometimes malignant, osteolytic tumor composed of multinucleated giant cells and ovoid or spindle-shaped cells, occurring most frequently in an end of a long tubular bone of young adults.
Synonym(s): giant cell myeloma, osteoclastoma.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

gi·ant cell tu·mor of bone

(jī'ănt sel tū'mŏr bōn)
A soft, reddish-brown, sometimes malignant, osteolytic tumor composed of multinucleated giant cells and ovoid or spindle-shaped cells; most frequent in young adults.
Synonym(s): osteoclastoma.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
They are osteoclastomas that are very similar both radiologically and histologically to giant cell granulomas, which are lesions that occur almost exclusively in the jaws.
Osteoclastomas, or giant cell tumors, are aggressive neoplasms but are usually not malignant.
Purification and characterization of a tartrate-resistant acid phosphatase from human osteoclastomas. Biochem J 1989;261: 601-9.