OspA


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OspA

The outer surface protein A of the spirochete Borrelia burgdorferi. It was formerly used as an antigen in Lyme disease immunization.
References in periodicals archive ?
'Thanks to the OSPA Travel Bursary, I will visit the Mona campus of the University of the West Indies in Jamaica where I hope to find further information on staffing and staff conditions,' she explained.
Depending on the culture in which the bacteria were grown, they may have OspC proteins, but are more likely to have OspA.
Figures 6 and 7 represent the OSPA distance and the corresponding standard deviation (dotted line) of extension states.
Caption: Figure 16: 1000 MC run average OSPA error versus time for simulated states and assimilated states.
For example, outer surface protein A (OspA), is a highly immunogenic lipoprotein that is expressed in the midgut of flat ticks, but is rapidly down-regulated upon onset of feeding, and is minimally expressed in the host.
Human granulCytic ehrlichiosis agent infection in a pony vaccinated with a Borrelia burgdorferi recombinant OspA vaccine and challenged by exposure to naturally infected ticks.
Figure 9 shows the number estimates and Figure 10 shows the accuracy statistic by the OSPA distance [18].
There is evidence that, in the bone marrow-derived macrophages, the OspA and OspB lipoproteins stimulate the production of superoxide anion radical and activate the inducible nitric oxide synthase (iNOS), responsible for the synthesis of a large amount of NO [2, 5, 6].
Sequence analysis of 16S, flaB, ospA, ospC, p66, and the 16S-23S intergenic spacer region (IGS) indicates the spirochetes are B.
To evaluate the error between the estimated and the true state, the Optimal Sub-Pattern Assignment (OSPA) is adopted as a multi-target miss-distance metric, which is described in detail in [24].