Osmium tetraoxide | definition of Osmium tetraoxide by Medical dictionary
osmium tetroxide (redirected from Osmium tetraoxide)
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os·mic ac·id (oz'mik as'id),
OsO4; a volatile caustic and strong oxidizing agent; colorless crystals, poorly soluble in water, but soluble in organic solvents; the aqueous solution is a fat and myelin stain and a general fixative for electron microscopy.
A volatile poisonous pale yellow solid, OsO4, with a pungent smell, used as an oxidizing agent and in solution to stain and fix biological material, especially lipids. Also called osmic acid.
osmium tetroxide or
osmic acid a substance used in the fixing of cytological preparations that is characterized by the small amount of distortion it causes.
References in periodicals archive
Constable, "Direct spectroscopic evidence for the formation of an asymmetric intermediate in the oxidation of alkenes by osmium tetraoxide
," Journal of the Chemical Society, Chemical Communications, no.
5; the SBS particles were dyed using osmium tetraoxide
. Figure 5a is the dispersion of SBS particles in SBS/PP system without the addition of CaC[O.sub.3] nanoparticles.
The material was fixed with 1% osmium tetraoxide
in the 0.1M sodium phosphate buffer and samples were processed as described previously (Sanchez 1999).
The pellets were washed in Pipes buffer with sucrose for 2 h at 4[degrees]C and postfixed in 1% osmium tetraoxide
in Pipes buffer for 75 min at 4[degrees]C.
They were then post-fixed with 1% osmium tetraoxide
and dehydrated in an increasing gradient of ethanol solutions.