osmium tetroxide

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os·mic ac·id

(oz'mik as'id),
OsO4; a volatile caustic and strong oxidizing agent; colorless crystals, poorly soluble in water, but soluble in organic solvents; the aqueous solution is a fat and myelin stain and a general fixative for electron microscopy.
Synonym(s): osmium tetroxide

osmium tetroxide

A volatile poisonous pale yellow solid, OsO4, with a pungent smell, used as an oxidizing agent and in solution to stain and fix biological material, especially lipids. Also called osmic acid.

osmium tetroxide


osmic acid

a substance used in the fixing of cytological preparations that is characterized by the small amount of distortion it causes.
References in periodicals archive ?
Constable, "Direct spectroscopic evidence for the formation of an asymmetric intermediate in the oxidation of alkenes by osmium tetraoxide," Journal of the Chemical Society, Chemical Communications, no.
5; the SBS particles were dyed using osmium tetraoxide. Figure 5a is the dispersion of SBS particles in SBS/PP system without the addition of CaC[O.sub.3] nanoparticles.
The material was fixed with 1% osmium tetraoxide in the 0.1M sodium phosphate buffer and samples were processed as described previously (Sanchez 1999).
The pellets were washed in Pipes buffer with sucrose for 2 h at 4[degrees]C and postfixed in 1% osmium tetraoxide in Pipes buffer for 75 min at 4[degrees]C.
They were then post-fixed with 1% osmium tetraoxide and dehydrated in an increasing gradient of ethanol solutions.