Orthopoxvirus


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orthopoxvirus

 [or´tho-poks-vi″rus]
any member of a genus of poxviruses, including the viruses that cause human smallpox and vaccinia.

Or·tho·pox·vi·rus

(ōr'thō-poks'vī-rŭs),
The genus of the family Poxviridae, which comprises the viruses of alastrim, vaccinia, variola, cowpox, ectromelia, monkeypox, and rabbitpox.

Orthopoxvirus

/Or·tho·pox·vi·rus/ (or´tho-poks-vi″rus) a genus of viruses of the subfamily Chordopoxvirinae (family Poxviridae) that cause generalized infections with a rash in mammals, including cowpox, monkeypox, and variola viruses.

orthopoxvirus

[or′thopoksvi′rus]
any member of a genus of poxviruses, including the viruses that cause human smallpox and vaccinia.

Or·tho·pox·vi·rus

(ōr'thō-poks'vī'rŭs)
The genus of the family Poxviridae that comprises the Alastrim, Vaccinia, Variola, Cowpox, Ectromelia, Monkeypox, and Rabbitpox viruses.

Orthopoxvirus

The genus of viruses that includes monkeypox, smallpox, cowpox, and camelpox.
Mentioned in: Monkeypox

Orthopoxvirus

a genus in the family Poxviridae.

O. infections
see pox.
References in periodicals archive ?
The last case of naturally acquired smallpox disease, caused by the orthopoxvirus variola virus (VARV), occurred in 1977, and the last laboratory-acquired case occurred in 1978.
7 Million challenge grant from the National Institutes of Health (NIH) to support the development of protease inhibitors to treat orthopoxvirus infections, such as smallpox and monkeypox.
The inoculation plan has caused some concern, since the vaccine uses live vaccinia, an Orthopoxvirus belonging to the family Poxviridae, which includes other viruses such as variola (smallpox) and cow pox.
On March 8, lesion specimens were analyzed at the Illinois Department of Public Health Laboratory (IDPHL) in Chicago by real-time polymerase chain reaction (PCR) orthopoxvirus generic assay and nonvariola orthopoxvirus assay.
DNA extracted from homogenates and virus isolated from the biopsy material were tested by orthopoxvirus real-time PCR (1); results were positive for all 6 samples.
Laboratory confirmation of orthopoxvirus infections, including vaccinia, requires test methods that are not commercially available.
Twenty-six states and DC (57%) reported their state public health laboratory could rapidly provide testing by orthopoxvirus nonvariola polymerase chain reaction (PCR) assay and viral culture ([dagger]); 22 (47%) could provide testing by orthopoxvirus PCR assay, 10 (21%) by a variola PCR assay, and seven (15%) by electron microscopy.
This is the first time we have data in primates that confirm a drug's potential activity against orthopoxvirus infections," Dr.
The 50% plaque-reduction neutralization test showed that the father, mother, and 14-year-old daughter had neutralizing antibodies against orthopoxvirus (titers 800, 3,200, and 800 neutralizing units/mL, respectively).
In electron microscopy, cell culture and tear fluid samples contained particles with typical orthopoxvirus (OPV) morphology.
One of the three was confirmed as having monkeypox; another person had two skin lesion specimens that tested negative for orthopoxvirus and varicella zoster virus at the state health laboratory; no specimens were obtained for the third person who reported a single, dime-sized, pruritic and erythematous skin les ion (not pusrular) remote from the vaccination site that appeared 4 days after vaccination and faded within a week.
Demonstration of virus morphologically consistent with an orthopoxvirus by electron microscopy in the absence of exposure to another orrhopoxvirus