opioid receptor

(redirected from Orphanin)

opioid receptor

any of a number of types of receptors for opiates and opioids. At least seven different types are postulated at different locations in the body, grouped into three major classes (delta, kappa, and mu) according to the specific substances they bind and to the specific physiological effect or effects that binding causes or inhibits.
References in periodicals archive ?
Cebranopadol is a first-in-class drug candidate due in large part to its unique ability to bind with high affinity to not only classical opioid receptors, but also the nociceptin/ orphanin FQ peptide, or NOP, receptors which may offer improved management of some pain states with decreased side effects.
University of Michigan (Ann Arbor, MI) has patented orphanin FQ receptor nucleic acid sequences.
In addition, a peptide known as nociceptin or orphanin FQ has actions at a separate opiate-like receptor called the ORL-1 receptor (Connor and Christie 1999).