opioid receptor

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opioid receptor

any of a number of types of receptors for opiates and opioids. At least seven different types are postulated at different locations in the body, grouped into three major classes (delta, kappa, and mu) according to the specific substances they bind and to the specific physiological effect or effects that binding causes or inhibits.
References in periodicals archive ?
45] Its ligand, the endogenous nociceptin/ orphanin FQ (N/OFQ) is 17 amino acid long and has resemblances with the endogenous ligand of the kappa opioid receptor dynorphin.
Structure-activity relationship studies on the novel neuropeptide orphanin FQ.
Localization of orphanin FQ (nociceptin) peptide and messenger RNA in the central nervous system of the rat.
Fos expression in feeding-related brain areas following intracerebroventricular administration of orphanin FQ in rats.
Global Markets Direct's, 'Nociceptin Receptor (Kappa-Type 3 Opioid Receptor or KOR-3 or Orphanin FQ Receptor or OPRL1 or OOR or ORL1) - Pipeline Review, H1 2016', provides in depth analysis on Nociceptin Receptor (Kappa-Type 3 Opioid Receptor or KOR-3 or Orphanin FQ Receptor or OPRL1 or OOR or ORL1) targeted pipeline therapeutics.
The report provides comprehensive information on the Nociceptin Receptor (Kappa-Type 3 Opioid Receptor or KOR-3 or Orphanin FQ Receptor or OPRL1 or OOR or ORL1), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
The report provides a snapshot of the global therapeutic landscape for Nociceptin Receptor (Kappa-Type 3 Opioid Receptor or KOR-3 or Orphanin FQ Receptor or OPRL1 or OOR or ORL1)
Leone A, Spatola GF, Cucco D, Tessitore in, orphanin and leptin in the major salivary glands of some mammals.
Nociceptin/ orphanin FQ (N/OFQ), the endogenous ligand of ORL(1), plays an important role in nociceptive transmission of neuropathic pain through its receptor.
Nociceptin, also called orphanin FQ (N/OFQ), is the natural ligand of the opioid receptor-like 1 receptor (ORL-1), and is classified as the fourth member of the opioid family of receptors and named OP(4).
University of Michigan (Ann Arbor, MI) has patented orphanin FQ receptor nucleic acid sequences.
In addition, a peptide known as nociceptin or orphanin FQ has actions at a separate opiate-like receptor called the ORL-1 receptor (Connor and Christie 1999).