ornithine decarboxylase


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or·ni·thine de·car·box·yl·ase

an enzyme catalyzing the decarboxylation of l-ornithine to putrescine and CO2; first step in polyamine biosynthesis.
References in periodicals archive ?
Posttranslational regulation of ornithine decarboxylase activity.
Similarly, 1, 2 and rutin showed weak activity on both aromatase inhibition and ornithine decarboxylase assays (Table 1).
Ornithine decarboxylase from Escherichia coli: stimulation of the enzyme activity by nucleotides.
Gerner of the University of Arizona, Tucson, to fight the development of cancer by targeting ornithine decarboxylase, a key polyamine pathway that acts as an instigator of growth.
monosperma on TAA-mediated hepatic oxidative stress, ornithine decarboxylase (ODC) activity and DNA synthesis, 30 male rats were randomly taken in five groups and application was done in the following manner:</p> <pre> Groups Treatment regimen I.
aureus by positive results for catalase and slide/tube coagulase and a negative result for ornithine decarboxylase.
SAGE analysis revealed the expression changes of genes related to lipid metabolism [crystalline, zeta (Cryz); phosphatidic acid phosphatase type 2c (PPap2c)], carbohydrate metabolism [phosphoglycerate kinase 1 (Pgk1); sorbitol dehydrogenase 1 (Sdh1)], and amino acid metabolism (glutamate dehydrogenase (Glud); ornithine decarboxylase, structural (Odc).
Currently under investigation are epigallocatechin gallate, a green tea catechin with antioxidant, sunscreen, and UVB signal transduction-blocking activity; perillyl alcohol, a monoterpene derived from citrus peel that inhibits Ras farnesylation; difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase and polyamines; retinoids that target retinoid X receptors and AP-1 activity; and nonsteroidal anti-inflammatory agents that inhibit cyclooxygenase and prostaglandin synthesis.
lugdunensis, with positive results for ornithine decarboxylase, trehalose, and a-pyrrolidonyl-13-naphthylamide.
Ornithine decarboxylase, a rate-limiting enzyme involved in the synthesis of polyamines, is also reduced by DAS (98,112,113), although there is evidence of an increase in the livers of rat not treated with initiators (114).
Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors.

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