According to the retention time of calibration standards (Table 1), aqueous and organic extracts of Origanum majorana presented the same chemical profile composed of 18 identified phenolic compounds present in some fractions and absent in the other.
Treatment of breast MDA-MB-231 and colon HT-29 human cancer cell lines for 72 h with increasing concentrations of extracts from Origanum majorana causes morphological changes (detached cells and loss of anchor properties) compared to untreated cells (cells attached to neighbors and preservation of anchor properties), revealing that both lines went through cell death with pronounced effect on MDA-MB-231 cells (data not shown).
Along with the prototype inhibitor of AChE physostigmine, obtained from the plant Physostigma venenosum, other molecules with highly significant anti-cholinesterase activity are huper-zine-A, galantamine, [alpha]-viniferin and ursolic acid obtained from Huperzia serrata, Galanthus nivalis and Narcissus sp., Caragana chamlague and Origanum majorana, respectively.
Inhibitory effect of ursolic acid purified from Origanum majorana L on the acetylcholinesterase.
The x between the two scientific names indicates that it's a cross between Origanum vulgare and Origanum majorana
, or sweet marjoram.
Mae ganddo flodau pinc/porffor ac yn aml iawn mi welwn ni rai sydd wedi dianc o'r ardd, penrhudd yr ardd (Origanum majorana
; pot majoram) yn tyfu'n wyllt.
This source: www.lehigh.edu/~jahb/herbs/smallherbs.html--says: "Marjoram comes in at least two types: the annual, sweet or knotted marjoram (Origanum majorana
), which is a small-leaved, low-growing annual, and the larger wild marjoram or oregano (Origanum vulgare) that is perennial but has a stronger, coarser flavor.
With the exception of sweet marjoram (Origanum majorana
), it is easy to grow and hardy and has delightful golden forms, Origanum vulgare `Aureum', O v `Gold Tip', and O v `Aureum Crispum'.
The seeds of medicinal plants were Plantago sp, Alyssum spp, Portulaca oleracea, Sesamum indicum, Origanum majorana
, Trigonella foenum, Anethum graveolens, Melilotus officinalis, Trachyspermum ammi, Cuminum cyminum, Lactuca sativa and Lallemantia royleana that collected from medical fields.
In this research, we cultured Origanum majorana as a new importation medicinal plant in Iran.
Previous study on essential oil composition in Origanum majorana showed that, terpinene-4-ol (38.4%), cis-sabinene hydrate (15.5%), p-cymene (7.0%) and [delta]-terpinene (6.9%), were the main components in this plant .