organotin

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organotin

Any tin-based organic compound in wide use for marine anti-fouling paints, wood catalysts, plasticisers, slimicides, in industrial water systems and as fungicides. Human exposure results from contaminated seafood, agricultural products and drinking water. Blood levels of organotins may be high enough to act on retinoid X receptors and PPAR gamma, upregulating the adipogenic signalling pathway, which explains organotins’ obesogenic effects.
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Moreover, in general, the biological activity of organotin compounds appears to be greatly influenced by the structure of the molecule and likely by the nuclearity of the complexes [16, 17].
Organotin compounds are highly lipophilic and readily penetrate the blood-brain barrier to enter the brain (Kotake 2012).
Further, concentrations of organotin compounds are high in ports and shipyards.
chocolata, we believe it would be advisable to use this species as a potential bioindicator of pollution by organotin compounds on the coast from northern Chile.
prohibition on the application of organotin compounds that act as
The mechanism of the neurotoxicity and underlying selective vulnerability of trimethyltin have not been fully elucidated it has been proposed that mitochondrial targeting of the organotin compounds leads to a change in local microenvironment in which TMT interacts with the protein Stannin, compromising the integrity of the mitochondrial membrane and initiating apoptosis (Billingsley et at.
Metallic tin is used to line the aerosols, beverages, and food cans, but organotin compounds are used in making food packagings, plastics, pesticides, paints, plastic pipes, and pest repellents, while inorganic tin is used in toothpastes, dyes, perfumes, soaps, food additives, and pigments in ceramic and textile industries [12].
The development of male characteristics, including a penis and vas deferens, in females of prosobranch gastropods is called "imposex" (Smith, 1971) which is mainly caused by organotin compounds tributyltin (TBT) and triphenyltin (TPhT).
Silpuran 4200 is formulated with a new catalyst that does not use organotin compounds, making it particularly safe to use from a health standpoint.
13) made a study on photodegradation of PVC with different types of thermal stabilizers, including metal stearates and three organotin compounds, by ESR analysis, which indicates that the organotin stabilizers are much more effective against photodegradation than the metal stearate stabilizers.
The concentrations of all organotin compounds were clearly higher (t-test, P < 0.