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To conclude, 3D organoid system transplantation renders obvious advantage over traditional approaches which probably focus on pure populations of particular stem cell-derived cell types.
It can begin to integrate these with other organoid systems in a way that captures the complex systems-level physiology of the human body.
(28) The stem cells have been successfully differentiated toward regional subtypes of neurons of the midbrain, forebrain, and hindbrain, as well as the formation of 3-dimensional organoid systems, allowing researchers to study a variety of neural diseases, including microcephaly.