LEP

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LEP

A gene on chromosome 7q31.3 that encodes leptin, a protein secreted by white adipocytes, which plays a key role in regulating body weight. By binding to its cognate receptor, leptin is part of a signalling pathway which inhibits food intake and regulates energy expenditure to maintain fat homeostasis. Leptin plays a role in the endocrine system, and is involved in regulating immune and inflammatory responses, haematopoiesis, angiogenesis, reproduction, glucose homeostasis, bone formation, and wound healing.

Molecular pathology
Mutations of LEP and/or its regulatory regions are linked to obesity, morbid obesity with hypogonadism, and type-2 diabetes.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Seth Marder and Steve Barlow from Georgia Tech, who led the development of the new dopant, called the ruthenium compound a "hyper-reducing dopant." They said it is unusual, not only its combination of electron donation strength and air stability, but in its ability to work with a class of organic semiconductors that have previously been very difficult to dope.
Charge Transport in Organic Semiconductors With Application to Optoelectronic Devices, PhD thesis, Jaume.
The other types of polymers that are needed in the fabrication of OSCs are acceptors (n-type organic semiconductors).
This result indicated that adding CNP into P3HT will disturb the crystal ordering of the organic semiconductor. In general, the decreasing of crystal ordering suppresses the carrier transportation.
Kim, "Interfacial doping for efficient charge injection in organic semiconductors" Physica Status Solidi (A), vol.
Using the ferroelectric biopolymer thin film and an organic semiconductor, the group has prototyped a 3x3-pixel-equivalent memory array screen-printed on a flexible plastic film and confirmed that the device retains a two-digit drain current on/off ratio for more than 10 days after power is turned off.
Elecon CEO, Ross Haghighat explained, "ELEFLEX(TM) organic semiconductors represent a revolution in the organic semiconductor field.
Inokuchi, 74, discovered that some organic compounds conduct electricity and became a pioneer in molecular electronics by developing an organic semiconductor. The Hiroshima Prefecture native is chief scientist of the Space Utilization Research Program at the National Space Development Agency of Japan.
The investment will build on the PS3m of investment from Finance Wales to date and will be used to further develop the leading scientific foundation of the SmartKem tru-FLEX organic semiconductor material range, and to accelerate this technology towards full commercialisation.
A company that develops organic semiconductor materials for flexible displays in smartphones and tablets has signed a joint development agreement with a major Asian manufacturer.