transplant rejection

(redirected from Organ rejection)

transplant rejection

Graft rejection, organ rejection, tissue rejection Immunology The constellation of host immune responses evoked when an allograft tissue is transplanted into a recipient; rejection phenomena may be minimized by optimal matching of MHC antigens and ABO blood groups and ameliorated with immunosuppressants–eg, cyclosporin, tacrolimus, rapamycin Exceptions of TR Corneal transplants, identical twins. See Graft-versus-host disease, HLA, MHC, Tissue typing.


1. an organ or tissue taken from the body and grafted into another area of the same individual or another individual.
2. to transfer tissue from one part to another or from one individual to another.

ovum transplant
see ovum transplant.
transplant rejection
References in periodicals archive ?
This Phase 3 clinical study is a 2-armed parallel group, prospective, randomized, open-label, multi-center, non-inferiority trial to establish the efficacy and safety of conversion from maintenance immunosuppressive therapy with Prograf[R] capsules twice daily to LCP-Tacro[TM]tablets once daily for the prevention of organ rejection in stable adult kidney transplant patients.
New Medication To Combat Organ Rejection In Kidney Transplant PatientsAnticipated To Be Available December 7, 2015
Novartis, East Hanover, NJ, announced the US Food and Drug Administration (FDA) has approved Zortress (everolimus) for the prophylaxis of organ rejection in adult patients receiving a liver transplant.
London, Sep 25 (ANI): A simple blood test can now help doctors in identifying the clues of transplant rejection-a feat that could pave the way for a non-invasive alternative for diagnosing organ rejection before damage occurs, says a new study.
Injected deep into living tissue, the new nanobauble could take the chemical pulse of a single cell, potentially signaling conditions such as cancer or organ rejection, the inventors suggest.
Therefore, TAFA93 has the potential to be administered as a complimentary therapy with ISA247 in the prevention of organ rejection after transplantation.
Cyclosporin, used by organ transplant recipients to prevent organ rejection, can cause an even more massive gum overgrowth.
Food and Drug Administration (FDA) for prophylaxis of organ rejection in patients who convert from immediate-release tacrolimus.
RAD001 is an investigational agent for the prevention of organ rejection with adult patients receiving a liver transplant.
Of the 115 transplant patients without infections, 39 had severe heart problems, including eight cases of strong organ rejection, within 3 months of a checkup.
About 75 percent of recipients survive the first year after the transplant, but infection and organ rejection reduce the survival rate by 5 percent each year after that, said a hospital spokeswoman.