sepsis syndrome

(redirected from Organ dysfunction)

sepsis syndrome

clinical evidence of acute infection with hyperthermia or hypothermia, tachycardia, tachypnea and evidence of inadequate organ function or perfusion manifested by at least one of the following: altered mental status, hypoxemia, acidosis, oliguria, or disseminated intravascular coagulation.

sepsis syndrome

clinical evidence of acute infection with hyperthermia or hypothermia, tachycardia, tachypnea and evidence of inadequate organ function or perfusion manifested by at least one of the following: altered mental status, hypoxemia, acidosis, oliguria, or disseminated intravascular coagulation.

sepsis syndrome

A constellation of signs, Sx, and systemic responses caused by a wide range of microorganisms that may eventuate into septic shock; SS is a systemic response to infection
Sepsis syndrome, defining parameters  
• Temperature Hypothermia < 35ºC–96ºF or hyperthermia > 39ºC–101ºF
• Tachycardia > 90 beats/minute
• Tachypnea > 20 breaths/minute
• Site of infection Clinically evident focus of infection or positive blood cultures
• Organ dysfunction 1+ end organs with either dysfunction or inadequate perfusion or cerebral dysfunction
• Metabolic derangement Hypoxia–PaO2 < 75 mm Hg, ↑ plasma lactate/unexplained metabolic acidosis
• Fluid imbalance Oliguria–< 30 mL/hr
• WBC counts < 2.0 x 109/L; > 12.0 x 109/L–US: < 2000/mm3; > 12 000/mm3
Note: The confusing semantics of the terms sepsis, sepsis/septic syndrome, and septic shock are unlikely to be resolved in the forseeable future; the terms sepsis and septic syndrome are essentially interchangeable and would in part overlap with septicemia–the early components of a pernicious infectious cascade that has spilled into the circulation; the term septic shock is used when the process becomes virtually irreversible.

sep·sis syn·drome

(sep'sis sin'drōm)
Clinical evidence of acute infection with hyperthermia or hypothermia, tachycardia, tachypnea, and evidence of inadequate organ function or perfusion manifested by at least one of the following: altered mental status, hypoxemia, acidosis, oliguria, or disseminated intravascular coagulation.

sep·sis syn·drome

(sep'sis sin'drōm)
Clinical evidence of acute infection with hyperthermia or hypothermia, tachycardia, tachypnea, and evidence of inadequate organ function.
References in periodicals archive ?
The first such indication Enlivex is targeting is prevention of cytokine storms and organ dysfunction associated with sepsis.
| 2009: Former South Korean president and 2000 Nobel Peace Prize recipient Kim Dae-jung died of multiple organ dysfunction syndrome.
The revised definition characterizes sepsis as a dysregulated host response to infection resulting in life-threatening organ dysfunction. But Sepsis-3 is based entirely on adult data and is not considered applicable to children.
A ready pocket reference rather than a comprehensive reference, it considers such topics as airway management and anesthesia, operating room practice and operative approaches, multiple organ dysfunction syndrome, laparoscopic treatment of the acute abdomen (emergency and trauma), and complications of tracheostomy and intubation.
Symptoms are high fever, chills, headache, jaundice, diarrhea, fatigue, sore throat, joint and muscle pains, rashes, reddish eyes, and abdominal pains to Weil's disease with organ dysfunction. Immediate medical attention is advised," the humanitarian organization said in a statement.
If the requirement for organ support was similar, did those patients who died do so without initial organ dysfunction, or did those who developed organ dysfunction have higher sepsis-related organ failure assessment (SOFA) scores and thus do worse?
A compensatory anti-inflammatory response syndrome (CARS) was proposed to encompass these control mechanisms: a balanced response could result in infection control and recovery from organ dysfunction, as a predominance of the inflammatory response leads to organ dysfunction and death, while a predominance of the anti-inflammatory response, the so-called immunosuppression of sepsis, could lead to the persistence of foci of infection or the development of new secondary or even opportunistic infections and subsequent death (18).
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection (Singer 2016).
67-year-old Kumar was suffering from multiple organ dysfunction syndrome for a long time and was under treatment for the last 8 months.
(1) The immune response to infection is a complex process, involving various types of cells and production of a cascade of cytokines, leading to cell damage and organ dysfunction. (2-4) T helper (Th) cells have long been recognized as vital components of the adaptive immune system.
Sepsis is a combination of suspected infection that is causally related to life-threatening organ dysfunction. And patients can manifest that organ dysfunction in a variety of ways, whether it's altered mental status, or difficulty breathing, or low blood pressure, or all of these togeth er, and as a result, clinicians may encounter a patient with sepsis, but vary in both how fast they recognize this, and in whether they even call them septic or not.