opsonin

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opsonin

 [op´sŏ-nin]
an antibody that renders bacteria and other cells susceptible to phagocytosis. adj., adj opson´ic.
immune opsonin an antibody that sensitizes a particulate antigen to phagocytosis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

op·so·nin

(op'sŏ-nin),
Any blood serum protein that binds to antigens, enhancing phagocytosis (for example, C3b of the complement system, specific antibodies).
[G. opson, boiled meat, provisions, fr. hepsō, to boil, + -in]
Farlex Partner Medical Dictionary © Farlex 2012

opsonin

(ŏp′sə-nĭn)
n.
An antibody or product of complement activation in blood serum that causes bacteria or other foreign cells to become more susceptible to the action of phagocytes.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

op·so·nin

(op'sŏ-nin)
A substance that binds to antigens, enhancing phagocytosis.
[G. opson, boiled meat, provisions, fr. hepsō, to boil, + -in]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

opsonin

One of a number of substances, especially an antibody, naturally present in the blood that bind to the surface of bacteria to make them more readily susceptible to attack and destruction by PHAGOCYTES.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

opsonin

a type of ANTIBODY which binds to ANTIGENS, increasing their susceptibility to phagocytosis by other antibodies.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
This PLGA-PEG-ligand combination provided two advantages, one was the hindering of opsonins deposition and the other was the preferential uptake of ovalbumin loaded NPs by DEC-205 receptors [188].
Foreign particles, such as microbial pathogens, can be recognized directly by receptors that bind molecules not found in higher organisms, or indirectly through opsonins. Several receptor types are found on a single phagocyte and they cooperate for recognition and ingestion of the particle.
This is by the presence of complement, antibodies and opsonins in serum.
More research should, therefore, be undertaken in that direction by targeting a range of humoral factors, such as other lysosomal enzymes (i.e., acid phosphatase), agglutinins, opsonins, or various antimicrobial peptides.
Apoptotic cells expose ectoCRT, phosphatidylserine, HSP70, HSP90, opsonins, thrombospondin, HMGB1, and other molecules that serve to eat-me signals for professional APCs, monocytes and macrophages recognition, and engulfment [34].
The permanence in the bloodstream of nanovehicles is strongly affected by physical interactions with specific blood circulating components, opsonins. These components prevalently include complement proteins such as C3, C4, and C5, laminin, fibronectin, C-reactive protein, type I collagen, and immunoglobulins [3].
The rationale for using uterine lavage in the treatment of uterine infections is based upon: 1) reduction of bacterial numbers and removal of exudates from the uterine lumen, 2) enhanced physical clearance of uterine contents by stimulation of uterine contractions and 3) recruitment of neutrophils and possibly opsonins by inducing transient irritation of the endometrium.
This elimination is due to the recognition by serum proteins (opsonins) and complement components which prime liposomes for macrophage removal from the circulation [21, 22].
Nonbiological particles lack specific opsonins preventing them from classic opsonin-dependent phagocytosis.
The opsonins perform a clearance function, whereas anaphylatoxins are involved in generation of the neuroinflammatory response [143].
In some cases plant lectins have been shown to be able to act as opsonins in invertebrate phagocyte systems, and concanavalin A receptors have been described on oyster hemocytes (Sami et al.