Opioids


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opioid

Neurology A pain-attenuating peptide that occurs naturally in the brain, which induces analgesia by mimicking endogenous opioids at opioid receptors in the brain. See Opioid-mediated analgesia system.
Opioids
Agonists The most potent opioid agonists are morphine, meperidine, methadone; other opioids include hydromorphine–Dilaudid®, codeine, oxycodone–Percodan®, propoxyphene–Darvon®
Antagonists Naloxone–Narcan®
Mixed agonsts-antagonists Pentazocine–Talwin® 

Opioids

One of the major classes of semi or fully synthetic psycho-active drugs that includes methadone.
References in periodicals archive ?
The Alternatives to Opioids (ALTO) in the Emergency Department Act would establish a demonstration program to test alternative pain management protocols to limit to use of opioids in hospital emergency departments.
In patients with stubborn back aches or hip or knee arthritis, opioids worked no better than over-the-counter drugs or other nonopioids at reducing problems with walking or sleeping.
The Justice Department will file a"statement of interest" in consolidated litigation on opioids.
Overall, nearly one-fourth of US high school seniors had some exposure to prescription opioids.
These figures are concerning in part because "a significant association between medical use of prescription opioids alone in adolescence and subsequent nonmedical use of prescription opioids was observed at age 35 years" in a national longitudinal study reported in the journal Pain (2016 Oct; 15 7[10]:2173-8), said Calista M.
We are experiencing the consequences of 20 years of medically prescribed opioids to control pain and dispensed for home use (Meldrum, 2016).
To assist construction companies, contractors, and other employers in addressing the opioid and prescription drug epidemic, it is important to understand the scope of the problem, how opioids affect the brain, and strategies for managing the use of these powerful drugs.
Although the illegal drug heroin is closely associated with opioid abuse, there are prescription opioids as well that can be addictive and might be abused.
The initiative includes limiting to seven days the supply of opioids dispensed for certain acute prescriptions for patients who are new to therapy, as well as limiting the daily dosage of opioids dispensed based on the strength of the opioid.
Drug overdoses, primarily from opioids, are now the leading cause of death for Americans under age 50.
This 15-year study of more than 1200 people with HIV in North Carolina found that 27% of them--more than one quarter--used prescription opioids episodically (at least 1 opioid prescription in at least 2 consecutive years) or chronically (an opioid prescription during at least half of the years in care).