Suspicious signs or lesions included local or general lymphadenopathy, dermatitis, alopecia, cutaneous ulcerations, onychogryphosis
, lameness, weight loss, ocular or nasal lesions, epistaxis, and anemia.
Although both HMS and PLS share the common pathogenomic features of PPK and severe periodontitis6,7 and are allelic variants of cathepsin C gene mutations6,8, a number of additional findings are reported in HMS including onychogryphosis
(curved nails), arachnodactyly (spider fingers/ elongated and slender shaped fingers and toes), acro-osteolysis (tappered pointed distal phalangeal ends due to osteolysis), pes planus (flat foot), occasionally hyperkeratotic psorisiform lesions with an erythematous background on the extensor surfaces of elbows and knees9,10,11,12 and rarely destructive arthritis of the wrists and shoulder joints.13
due to biomechanical trauma from narrow-toed shoes with secondary onychomycosis is a frequently missed diagnosis, Dr.
A ABNORMAL thickening, hardening and curving of nails is called onychogryphosis
. It tends to occur in elderly people, but the reason is unknown.
Dogs were classified as either asymptomatic (no signs suggestive of disease) or symptomatic (the presence of at least one sign of VL infection such as dermatologic and ophthalmic disorders, lymphadenomegaly, splenomegaly, onychogryphosis
, apathy, or severe loss of weight) (COURA-VITAL et al., 2011; ALMEIDA et al., 2013).
On the causes of congenital onychogryphosis
. Mcn Med Wochenschr.
Animals were classified as symptomatic (showing clinical signs of leishmaniasis, such as weight loss, cachexia, dermatologic alterations, onychogryphosis
, lymphadenopathy, or kerato conjunctivitis) or asymptomatic (no clinical signs).
On the cause of congenital onychogryphosis
. Mcn Med Wonchenschr.
The VL in dogs is considered a chronic disease characterized by the emergence of several clinical signs such as lymphadenomegaly, dermatopathies (SOLANOGALLEGO et al., 2009), hepatosplenomegaly, onychogryphosis
(ALBUQUERQUE et al., 2007) and ophtalmopathies (BRITO et al., 2006).
(3,4) A surveillance study of 25,000 patients with onychogryphosis
showed 23% were over the age of 60 years (4).
Ingrowing toenail and onychogryphosis
. J Bone Joint Surg.