ondansetron


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Related to ondansetron: ondansetron HCl

antiemetic

 [an″te-e-met´ik]
1. useful in the treatment of vomiting.
2. an agent that relieves vomiting.

ondansetron

(ŏn-dăn′sĭ-trŏn′)
n.
A selective serotonin receptor antagonist, C18H19N3O, used in its hydrochloride form to prevent nausea and vomiting, especially when occurring postoperatively or as a result of chemotherapy or radiotherapy.

ondansetron

Oncology A selective serotonin S3 receptor antagonist used to ameliorate chemotherapy-induced N&V. See Chemotherapy-induced emesis.

ondansetron

A serotonin antagonist drug used to relieve nausea and vomiting caused by anticancer chemotherapy and radiotherapy and to prevent sickness after surgery. A brand name is Zofran.
References in periodicals archive ?
Conclusion: Postoperative nausea and vomiting is significantly lower in ondansetron and dexamethasone combination group as compared to ondansetron alone group after elective laparoscopic cholecystectomy.
The researchers found that ondansetron exposure increased from less than 1 percent before 2000 to 13 percent in 2013 to 2014 among women in the control group.
There have been two studies that have suggested an increased risk in specific major birth defects with first-trimester ondansetron use.
Conclusion: No association of anti-emetic efficacy of ondansetron with 18792A>G polymorphism in the target gene of 5-hydroxytryptamine type 3 subtype B was found.
The patients could request antiemetic and opioid analgesic medications, and the doses were recorded as well as the level of satisfactory reduction of PONV (0 = no symptoms; 1 = mild: few symptoms and not requiring treatment; 2 = moderate: presented symptoms and needed ondansetron 8 mg iv; 3 = severe: persisted symptoms after received ondansetron 8 mg iv and needed re-administration of ondansetron 8 mg iv).
Keywords * Ondansetron * Hyperpigmentation * Fixed drug eruption * 5HT3 receptor antagonists
To determine whether the contaminated lots of ondansetron harbored the same fungal strains as infected patients, we used WGST.
The active pharmaceutical ingredient in Zuplenz, ondansetron, belongs to a class of medications called serotonin 5-HT3 receptor antagonists and works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.
When used in combination with ondansetron and palonosetron, dexamethasone (8-11) was reported to be effective in reducing PONV.