Oncovirinae


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On·co·vir·i·nae

(ong-kō-vir'i-nē),
Term formerly used to designate a now obsolete subfamily of viruses (family Retroviridae) composed of the RNA tumor viruses that contain two identical plus-stranded RNA molecules. Subgroups are based on antigenicity, host range, and kind of malignancy induced (avian, feline, hamster, or murine leukemia-sarcoma complex; murine mammary tumor virus; primate oncoviruses). Like other retroviruses, they contain RNA-dependent DNA polymerases (reverse transcriptases). An important aspect of these viruses seems to be use of viral reverse transcriptase to make DNA that can be integrated into the DNA of the host cell and will replicate along with cellular DNA.
See also: retrovirus.
Farlex Partner Medical Dictionary © Farlex 2012

On·co·vir·i·nae

(ong'kō-vir'i-nē)
A subfamily of viruses (family Retroviridae) composed of the RNA tumor viruses that contain two identical plus stranded RNA molecules.
Synonym(s): oncornaviruses.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
El virus linfotropico humano tipo I (HTLV-I) es un retrovirus incluido dentro del grupo HTLV, STLV, BLV de la subfamilia Oncovirinae. Se asocia, sobre todo, con la leucemia de celulas T del adulto (ATL, por las siglas en ingles) (1-5) y la paraparesia espastica tropical/mielopatia asociada con la infeccion por HTLV-I (PET/HAM) (6-21), aunque cada dia son mas fuertes las asociaciones con otras entidades clinicas como uveitis, artropatias, dermatitis infecciosa y la polimiositis (16).