oncofetal antigens


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on·co·fe·tal an·ti·gens

tumor-associated antigens present in fetal tissue and some malignant tumors but not in normal adult tissue, including α-fetoprotein.

on·co·fe·tal an·ti·gens

(on'kō-fē'tăl an'ti-jenz)
Tumor-associated antigens present in fetal tissue but not in normal adult tissue, including α-fetoprotein and carcinoembryonic antigen.
References in periodicals archive ?
"The results of this preclinical work with ADXS-HOT represent an exciting opportunity that may allow us to develop disease-specific immunotherapies that have the potential to be effective against multiple targets, capable of generating high-avidity T cells against shared of public mutations, as well as multiple proprietary highly immunogenic cancer-testes and oncofetal antigens for multiple tumor types," said Robert G.
Two of the analytes examined, CA15-3 and CA125, showed atypical patterns of expression during the first year of life given their suspected status as oncofetal antigens (Fig.
Hepatocellular carcinomas in dogs have been separated from cholangiocarcinomas on the basis of their immunohistochemical staining patterns for oncofetal antigens in one report [24].