oligodendroglioma

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oligodendroglioma

 [ol″ĭ-go-den″dro-gli-o´mah]
a neoplasm derived from and composed of oligodendroglia.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

ol·i·go·den·dro·gli·o·ma

(ol'i-gō-den'drō-glī-ō'mă),
A relatively rare, relatively slow-growing glioma derived from oligodendrocytes that occurs most frequently in the cerebrum of adult humans; the neoplasm is grossly homogeneous, fairly well circumscribed, moderately firm, and somewhat gritty in consistency with interstitial calcification sufficiently dense so as to be detected by x-ray imaging of the skull. Microscopically, an oligodendroglioma is characterized by numerous small, round or ovoid, oligodendroglial cells with small, deeply stained nuclei (rarely observed in mitosis), and palely stained, indistinct cytoplasm; the neoplastic cells are rather uniformly distributed in a sparse, fibrillary stroma with scattered calcific bodies and an often prominent arcuate vasculature; chemoresponsiveness is associated with loss of heterozygosity on chromosome 1p and 19q.
[oligo- + G. dendron, tree, + glia, + -oma]
Farlex Partner Medical Dictionary © Farlex 2012

ol·i·go·den·dro·gli·o·ma

(ol'i-gō-den'drō-glī-ō'mă)
A rare, slowly growing glioma derived from oligodendrocytes that occurs most frequently in the cerebrum of adults.
[oligo- + G. dendron, tree, + glia, + -oma]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

oligodendroglioma

A slowly growing tumour of the nervous system derived from neural connective tissue cells, the oligodendroglial cells. The cells of the tumour are small, well-defined ‘halo cells’ with round nuclei and clear CYTOPLASM.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Chromosome 1p loss evaluation in anaplastic oligodendrogliomas. Neuropa thology.
Oligodendroglioma: incidence and biological behavior in a defined population.
Calcification was seen in tuberous sclerosis, neurocysticercosis, meningiomas, oligodendrogliomas, arteriovenous malformations and dermoid cyst.
Mutations of TP53 are found in more than 60% to 80% of infiltrative astrocytomas, anaplastic astrocytomas, and secondary GBMs, yet are rare in oligodendrogliomas. (8, 20, 21) The vast majority of diffuse astrocytomas that have IDH mutations also harbor a TP53 mutation.
Astrocytomas, oligodendrogliomas and metastatic carcinoma account for most cerebral hemispheric tumors.
(5, 6) Bannykh et al (5) demonstrated that most oligodendrogliomas, and a large fraction of astrocytomas and glioblastomas, expressed SOX10, correlating with our results.
Immunohistochemical studies are helpful in distinguishing oligodendrogliomas from other CCTs of the CNS.
As constitute 10%-11% of glial tumors and it is known through the new classification that the genetic alterations that differentiate grade II-III astrocytic tumors from oligodendrogliomas are p53 and alpha thalassemia/mental retardation syndrome (ATRX) mutations (4).
Greg Jenkins has been battling the rare condition oligodendroglioma since 2010, when he took an unexpected seizure while driving his car in Edinburgh.
Two cases of astrocytomas were diagnosed as oligodendrogliomas [Figure 4a and b].
Oligodendrogliomas are common intra-axial primary brain tumours, and carry special significance due to several key features, which when present provide better prognosis compared to other intra-axial tumours.
In this classification scheme, oligodendrogliomas are divided into two forms: the well-differentiated oligodendroglioma and the less common anaplastic oligodendroglioma.