oligodendrocyte

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Related to Oligodendrocytes: microglia, Astrocytes, Satellite cells, Ependymal cells

oligodendroglia

 [ol″ĭ-go-den-drog´le-ah]
1. the non-neural cells of ectodermal origin forming part of the adventitial structure of the central nervous system.
2. the tissue composed of such cells.

ol·i·go·den·dro·cyte

(ol'i-gō-den'drō-sīt),
A cell of the oligodendroglia.

oligodendrocyte

/ol·i·go·den·dro·cyte/ (-den´dro-sīt) a cell of the oligodendroglia.

oligodendrocyte

(ŏl′ĭ-gō-dĕn′drə-sīt′, ō′lĭ-)
n.
One of the cells comprising the oligodendroglia.

oligodendrocyte

[ol′igōden′drəsīt]
Etymology: Gk, oligos + dendron, tree, kytos, cell
a type of neuroglial cell with dendritic projections that coil around axons of neural cells. The projections continue as myelin sheaths over the axons.

ol·i·go·den·dro·cyte

(ol'i-gō-den'drō-sīt)
A cell of the oligodendroglia.
Enlarge picture
OGLIODENDROCYTE

oligodendrocyte

(ol?i-go-den'tro-sit) [? + ? + kytos, cell]
A glial cell found most commonly in axon tracts; it myelinates axons in the central nervous system just as Schwann cells myelinate axons in the peripheral nervous system. Oligodendrocytes are neuroectodermal cells that originate from different precursors in the neural tube than astrocytes; later, stem cells in the subependymal layer can continue to generate new oligodendrocytes. Mature oligodendrocytes wrap neighboring axons in myelin, and some oligodendrocytes can simultaneously wrap many axons. However, not all oligodendrocytes myelinate axons.
Synonym: oligodendroglia See: illustration

oligodendrocyte

A connective cell of the central nervous system (glial cell) that participates in the formation of the myelin sheaths of nerve cell axons.

oligodendrocyte

a cell of oligodendroglia.
References in periodicals archive ?
In previous UCSF research employing high-throughput drug-screening technology that Chan designed, he and colleagues discovered a cluster of compounds, all of which target proteins known as muscarinic receptors, that promote remyelination the process by which cells known as oligodendrocytes will rewrap themselves around axons to repair the myelin sheath.
Caption: Stained glass cells In this zoomed-in image of the optic nerve, oligodendrocytes glow in various colors, allowing scientists to identify individual cells.
They found that when a muscarinic type 3 receptor on human oligodendrocyte progenitor cells was activated, differentiation was completely blocked.
This will allow us to look for therapies affecting not just motor neurons but also oligodendrocytes," says Lucie Bruijn, PhD, chief scientist, ALS Association.
Until now, OPCs and oligodendrocytes could only be obtained from fetal tissue or pluripotent stem cells.
Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement.
After immunostaining, the differentiated cells were identifed as neurons, astrocytes, and oligodendrocytes (Figure 2).
For MBP to enter myelin so rapidly, not only MBP mRNA, but also all other components needed for its translation, must be transported from the oligodendrocyte soma to each myelin sheath assembly site.
Multiple sclerosis occurs when the immune system attacks and kills myelin-forming oligodendrocytes, impeding nerve transmission and causing a variety of symptoms, including vision loss, numbness, muscle weakness and spasticity, mood swings, and cognitive decline.
Radiation obliterates cells that mature into oligodendrocytes, a type of cell that insulates the message-carrying part of nerve cells.
They also developed an accelerated protocol to induce these stem cells into becoming oligodendrocytes, the myelin-forming cells of the central nervous system implicated in multiple sclerosis and many other diseases.
This immune inflammation also damages oligodendrocytes, the type of cell that manufactures and repairs myelin.