Ohtahara syndrome

An early onset, extremely debilitating progressive epileptic encephalopathy characterised by tonic spasms, partial seizures and burst activity on electroencephalography
Management Ohtahara syndrome responds poorly to anticonvulsants and steroids
Prognosis Dismal
Well known patient Ivan, son of UK Prime Minister David Cameron, died of Ohtahara syndrome in 2009 at age 6

Ohtahara syndrome

(o-ta-ha'ra)
[S. Ohtahara, Japanese pediatric neurologist]
A form of progressive epileptic encephalopathy in newborns. The disease is difficult to treat and has a poor prognosis. Synonym: early infantile epileptic encephalopathy with suppression bursts
References in periodicals archive ?
After tests in hospital Archie, who is now 18 months old, from Llanrug near Caernarfon, was diagnosed with Ohtahara Syndrome, a severe form of epilepsy.
Calla was born with health issues including Ohtahara syndrome - a rare form of epilepsy.
Three-year-old Callum suffers from Ohtahara syndrome - a rare epilepsy condition - and was referred to Ty Hafan in 2013.
Ivan lived with cerebral palsy and a rare and severe form of epilepsy known as Ohtahara syndrome.
And the Prime Minister's first child, Ivan, was born with Ohtahara syndrome, a rare form of cerebral palsy and epilepsy.
Ohtahara syndrome which is one of the severe epileptic encephalopathy pictures observed in newborns was defined in 1976 for the first time.
That's because 14-year-old Connor suffers from Ohtahara syndrome - a very rare and extreme complication of epilepsy - which has left him disabled for life.
Ohtahara syndrome is a rare neurological disorder of infancy, which consists of frequent generalized seizures and continuous abnormalities on electroencephalogram.
Ivan had a rare epilepsy condition accompanied by severe cerebral palsy called Ohtahara Syndrome.