pilocarpine

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pilocarpine

 [pi″lo-kahr´pin]
a cholinergic alkaloid from leaves of Pilocarpus jaborandi and P. microphyllus; used topically in the eye as the base or the hydrochloride or nitrate salt as an antiglaucoma agent and miotic; the hydrochloride salt is also used orally to treat mouth dryness resulting from radiotherapy or associated with Sjögren's syndrome. The nitrate salt has also been administered by iontophoresis to produce sweating in a test for cystic fibrosis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

pi·lo·car·pine

(pī'lō-kar'pēn),
An alkaloid obtained from the leaves of Pilocarpus microphyllus or P. jaborandi (family Rutaceae), shrubs of the West Indies and tropical America; a parasympathomimetic agent used experimentally to induce seizures externally as a miotic and in the treatment of glaucoma; used as the hydrochloride and the nitrate salts.
[G. pilos, a felt hat, + karpos, fruit]
Farlex Partner Medical Dictionary © Farlex 2012

pilocarpine

(pī′lō-kär′pēn′)
n.
A colorless or yellow poisonous compound, C11H16N2O2, obtained from the leaves of the jaborandi and used to induce sweating, promote salivation, and treat glaucoma.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

pilocarpine

Therapeutics An alkaloid with mild β-adrenergic activity which, topically, ↓ intraocular pressure in glaucoma; it stimulates glands, resulting in diaphoresis, salivation, lacrimation it may be used to treat post-radiation or opioid-induced xerostomia, gastric and pancreatic secretion
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

pi·lo·car·pine

(pī'lō-kahr'pēn)
An alkaloid obtained from the leaves of Pilocarpus microphyllus or P. jaborandi, shrubs of the West Indies and tropical Americas; a parasympathomimetic agent used experimentally to induce seizures externally as a miotic and in the treatment of glaucoma.
[G. pilos, a felt hat, + karpos, fruit]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

pilocarpine

A drug used in the form of eye-drops to treat GLAUCOMA. Pilocarpine causes extreme constriction of the pupils so that traction is exerted on the root of the iris so as to open up the drainage channels for aqueous humour. The drug is on the WHO official list. Brand names are Minims pilocarpine, Pilogel, Salagen, Sno Pilo, and, in the form of a sustained-release insert placed behind an eyelid and left for a week at a time, Ocusert Pilo.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

pilocarpine 

An alkaloid obtained from the leaves of Pilocarpus microphyllus and other species of Pilocarpus. It is a parasympathomimetic (direct-acting cholinergic) drug, which mimics the effect of acetylcholine causing miosis and accommodation. It counteracts sympathomimetic mydriatics. It is used in the treatment of glaucoma. Pilocarpine hydrochloride is most commonly applied to the eye as a 1% solution. Carbachol and bethanechol chloride are other parasympathomimetic drugs with similar effects to pilocarpine. See parasympathomimetic drug; physostigmine.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann

pi·lo·car·pine

(pī'lō-kahr'pēn)
An alkaloid used experimentally to induce seizures externally as a miotic and to treat glaucoma.
[G. pilos, a felt hat, + karpos, fruit]
Medical Dictionary for the Dental Professions © Farlex 2012