POU2F1

(redirected from Octamer transcription factor)
Also found in: Wikipedia.

POU2F1

A gene on chromosome 1q24.2 that encodes a ubiquitous transcription factor which binds to and activates the promoters of genes for small nuclear RNAs (snRNA), as well as for histone H2B and immunoglobulins. It modulates transcription transactivation by NR3C1, AR and PGR.
References in periodicals archive ?
The 5'-proximal region of the Nos2 gene (region I) contains a TATA box and binding motifs for octamer transcription factor (OCT) and nuclear factor [kappa]B (NF-[kappa]B), which primarily mediate the transcriptional activation induced by LPS [23, 24, 31-33].
The Octamer Transcription Factor Binding Site Is Involved in the IL-4-Mediated Inhibition of Nos2 Gene Expression.
Roeder, "The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors," The Journal of Biological Chemistry, vol.