A group of 25 off-types and eight internal reference samples derived from Tifway (Table 1) were analyzed by DAF with the same set of 11 octamer
The scientists speculate that the DNA helix, coiled like a spring, wraps around the histone octamer
and holds the three sections together.
In addition to its two anti-cancer compounds, which have been highly active against tumor cells both in vitro and in vivo, Octamer
has also developed a compound that represents a new class of therapeutic agents directed against AIDS.
Rapid detection of octamer
binding proteins with "mini-extracts" prepared from a small number of cells.
Patent and Trademark Office has recently awarded Octamer
four patents which cover a new class of anti-tumor and anti-retroviral agents recently discovered in Octamer
The capacity for self-renewal and the pluripotency of ESCs is known to be controlled by the transcription factors, Nanog homeobox (NANOG), octamer
binding transcription factor-4 (OCT4) and sex determining region-Y box-2 (SOX2), and signaling pathways like leukemia inhibitory factor (LIF)-signal transducer and activator of transcription 3 (STAT3) and bone morphogenic protein (BMP)-Mothers against decapentaplegic homolog (SMAD) 1/4/5/8 (Rodda et al.
The basic unit of chromatin, a nucleosome, consists of four histone protein subtypes that form an octamer
around which the DNA is wrapped (Jenuwein and Allis 2001; Smith 1991).
Each nucleosome contains 146 bp DNA wrapped around an octamer
of core histones.
5 [micro]g) from the frontal cortex biopsy specimen was treated with DNase I (Ambion DNA-free; Austin, TX, USA) and reverse transcribed by using Superscript II (Invitrogen, Carlsbad, CA, USA) with random octamer
primers linked to an arbitrary defined 17-mer primer sequence (Eurofins MWG Operon, Huntsville, AL, USA).
The flexible and dynamic structure of the nucleosomel organization is facilitated by ATP-dependent chromatin-remodeling complexes that cause uncoupling of the close DNA-histone connection, the transfer of a histone octamer
to another DNA molecule, or the core particle to slide along the DNA (3, 4).
The histone that forms the nucleosome core complex is an octamer
formed by H2A, H2B, H3 and H4 while histone H1 is the linker histone that links the two nucleosomes.
Primary cardiac sarcomas may develop from resident or bone marrow-derived mesenchymal stem cells" use of immunohistochemistry including CD44 and octamer
binding protein 3/4.