LEP

(redirected from Obesity factor)
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LEP

A gene on chromosome 7q31.3 that encodes leptin, a protein secreted by white adipocytes, which plays a key role in regulating body weight. By binding to its cognate receptor, leptin is part of a signalling pathway which inhibits food intake and regulates energy expenditure to maintain fat homeostasis. Leptin plays a role in the endocrine system, and is involved in regulating immune and inflammatory responses, haematopoiesis, angiogenesis, reproduction, glucose homeostasis, bone formation, and wound healing.

Molecular pathology
Mutations of LEP and/or its regulatory regions are linked to obesity, morbid obesity with hypogonadism, and type-2 diabetes.

LEP

low egg passage, with reference to virus attenuation usually for vaccine production.
References in periodicals archive ?
This concept of eating too much and moving around too little is actually one of the most observable and significant child obesity factors.
In a survey conducted to gauge the influence of parents on their children's obesity factors, specifically physical activity levels and eating behaviors, 127 parents of second-, third- and fourth-graders answered questions to determine whether they recognized obesity factors in their children and could correctly classify their child's weight status.
Overweight and obesity factors contributing to obesity: Biological, behavioral and environmental factors associated with overweight and obesity.
Monitoring the child and family who are positive for a number of obesity factors allows early intervention for prevention of obesity.