Rela(redirected from OTTHUMP00000233476)
RELAA gene on chromosome 11q13 that encodes a protein that binds to NFKB1 or NFKB2 to form the NFKB complex (the most abundant form is NFKB1/RELA), which is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB); NFKBIA or NFKBIB inactivate the NFKB complex by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA or IKBKB)
marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Rela®Carisoprodol & meprobamate
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.