EGFR

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EGFR

Farlex Partner Medical Dictionary © Farlex 2012

EGFR

A gene on chromosome 7p12 that encodes epidermal growth factor, a transmembrane glycoprotein of the protein kinase superfamily, which is a receptor for members of the epidermal growth factor family. Binding of the protein to a ligand induces receptor dimerisation and tyrosine autophosphorylation and leads to cell proliferation.

Molecular pathology
EGFR mutations are associated with lung cancer.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

EGFR

Abbreviation for epidermal growth factor receptor.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

eGFR

estimated glomerular filtration rate.
Medical Dictionary, © 2009 Farlex and Partners