PDLIM2(redirected from OTTHUMP00000205199)
PDLIM2A gene on chromosome 8p21.3 that encodes an adapter protein located at the actin cytoskeleton, which promotes cell attachment. PDLIM2 overexpression enhances cell adhesion to collagen and fibronectin and
suppresses anchorage-independent growth, and it thus is thought to play a role in tumour cell migration.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.