MEIS1(redirected from OTTHUMP00000198326)
MEIS1A gene on chromosome 2p14 that encodes Meis homeobox 1, a homeobox protein belonging to the three amino acid loop extension (TALE) family of homeodomain-containing proteins. Meis homeobox 1 is a transcriptional regulator of PAX6 and transcriptional activator of PF4 when complexed with PBX1 or PBX2; it is required for hematopoiesis, megakaryocytopoiesis and vascular development.
Meis homeobox 1 may be a cofactor for HOXA7 and HOXA9 in inducing myeloid leukaemias.
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