IRF1

(redirected from OTTHUMP00000198266)

IRF1

A gene on chromosome 5q31.1 that encodes interferon regulatory factor 1, a protein of the interferon regulatory transcription factor (IRF) family, which activates interferon (IFN) alpha and beta transcription, and acts as a transcription activator of genes induced by IFNs alpha, beta and gamma. IRF1 also plays a role in regulating apoptosis and tumour-suppression.
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