OSRC | definition of OSRC by Medical dictionary
RB1 (redirected from OSRC)
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RB1 A gene on chromosome 13q14.2 that encodes a tumour suppressor protein which is a key regulator of entry into cell division, promoting G0-G1 transition following phosphorylation by CDK3/cyclin-C. RB1 represses transcription of E2F1 target genes. Underphosphorylated,
active forms of RB1 interact with E2F1 and repress its transcription activity, leading to cell cycle arrest. With calcium influx, RB1 is dephosphorylated by calcineurin, leading to release of the repressor complex.
Defects in RB1 cause childhood retinoblastoma, some forms of osteogenic sarcoma and increased susceptibility to bladder cancer.
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References in periodicals archive
In response to public concerns regarding the use of dispersants during the OSRC, the U.S.
Given the lack of epidemiologic research into the effects of dispersant exposure on human health, our study used data from a large cohort of workers participating in the Deepwater Horizon OSRC to assess two related objectives.
Sanford recently decided to leave the Conservation Commission to devote more time and energy to the OSRC.
The plan will give us a five-year action plan but, frankly, I see this effort extending well beyond that and the OSRC staying active well into the future.
By providing institutional financial aid, MVNC and ONU are very price competitive with OSRC
workforce included individuals from the Gulf states and across the United States and comprised oil industry workers, Coast Guard and other government personnel, temporarily out-of-work fishermen participating in the Vessels of Opportunity program, individuals looking for work, and volunteers.