ORX


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ORX

Abbreviation for orexin.
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In the present study, increased urinary DPD and elevated plasma TRAP activity seen in the ORX group was an indicative of elevated bone resorption.
Abnormalities in bone remodeling after ORX might have been the reason for increased fracture rate observed in the ORX group.
The aim of the experiments presented here was to investigate if the rhythms in neural activity in areas of the brain containing ORX persist under constant conditions in a diurnal rodent, and also to determine if ORX neurons might receive projections from the SCN in the diurnal grass rat and in the nocturnal lab rat.
Experiment 1: Patterns of Fos expression in neurons expressing ORX in constant darkness
Tissue was then processed for ORX by incubating first in normal horse serum (NHS, Vector) and then in the primary antibody goat anti-ORX B (Santa Cruz, 1:60,000) and the biotinylated secondary horse anti-goat (Vector, 1:200), with 3X10 min rinses between incubations.
For each section, the number of cells containing ORX (both single and double labeled), double labeled cells, and cells expressing Fos but not labeled for ORX were unilaterally drawn and counted in each of the three areas (medial, central, and lateral).
In the case of the percentage of ORX cells expressing Fos a two-way ANOVA was not performed because of lack of homogeneity of the variance even after standard transformations were used.
A correlational analysis was used to determine the relationship between Fos expression in and outside ORX neurons.
The present results demonstrated that although ORX lowered antioxidant capacity, plasma antioxidant status in the ORX group was still adequate to protect RBC against free radical-induced hemolysis.
Plasma concentration of IGF-I in rats drinking cranberry juice was not different from those of the ORX group suggesting that cranberry juice at the dosage given has no beneficial effect on bone formation.
The loss of the protective effect of testosterone on bone remodeling may have been the reason for increased fracture rate observed in the ORX group.
The effects of drinking cranberry juice for 4 months on antioxidant status, femoral quality, and calcium and magnesium concentrations in femur of orchidectomized rats Variable SHAM ORX Initial body 468 [+ or -] 13 450 [+ or -] 10 weight (g) Final body 580 [+ or -] 11 573 [+ or -] 11 weight (g) Food intake (g) 22 [+ or -] 0.