ONECUT2

ONECUT2

A gene on chromosome 15q21.3 that encodes a homeobox-type transcription activator, which binds to specific DNA sequences and stimulates expression of target genes—e.g., those involved in melanocyte and hepatocyte differentiation.
References in periodicals archive ?
Liu et al., "MiR-429 inhibits cells growth and invasion and regulates EMT-related marker genes by targeting Onecut2 in colorectal carcinoma," Molecular and Cellular Biochemistry, vol.
coli); ESTG2308609 (no HUGO ID available); DLX5, distal-less homeobox 5; NPBWR1(formerly GPR7), neuropeptides B/W receptor 1; APBA2, amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like); SLC32A1, solute carrier family 32 (GABA vesicular transporter), member 1; SLITRK1, SLIT and NTRK-like family, member 1; KCTD12, potassium channel tetramerisation domain containing 12; ONECUT2, one cut homeobox 2; RNF4, ring finger protein 4; SMAD7, SMAD family member 7.
ONECUT2 (One Cut Homeobox 2), RC3H1 (Ring Finger and CCCH-Type Domains 1), and SLC1A2 (Solute Carrier Family 1 Member 2) were regulated by 19 upregulated miRNAs; ONECUT2 and RAB6B (Member RAS Oncogene Family) were regulated by 11 downregulated miRNAs.