oral glucose tolerance test

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oral glucose tolerance test



A screening test for diabetes mellitus (DM), in which plasma glucose levels are measured after the patient consumes an oral glucose load. In screening patients for type 2 DM, measuring fasting plasma glucose levels or checking a hemoglobin A1c level is generally preferable to an OGTT because the former tests are simpler, cheaper, and better tolerated by patients. An OGTT reveals type 2 DM when plasma glucose levels exceed 200 mg/dl 2 hr after drinking a 75-g glucose load. Plasma glucose levels between 140 mg/dl and 199 mg/dl suggest impaired glucose tolerance.

Gestational Diabetes Mellitus

In pregnancy, a modified OGTT is used to screen women with risk factors for gestational diabetes (GDM), including obesity, family history of type 2 DM, age greater than 25 years, and a history of unexplained stillbirths. At 24 to 28 weeks' gestation, a 50-g glucose load is given; 1-hr plasma glucose levels greater than 140 mg/dl constitute a positive screening result. Any patient having a positive test result should then undergo a 2-hr, 100-g OGTT to determine whether GDM is present. See: table

Screen high-risk women at first visit, and screen all women at 24–28 weeks' gestation with 75g oral glucose tolerance test. American Diabetes Association revised Standards of Medical Care, published in Diabetes Care special supplement, January 2011. International Association of Diabetes and Pregnancy Study Groups published in Leary, J. et al. (2010). Best Practice Research Clinical Endocrinology and Metabolism 24 (4), 673.
Time:Glucose level exceeds:
Fasting92 mg/dl
60 min180 mg/dl
120 min155 mg/dl
180 min140 mg/dl

oral glucose tolerance test

glucose tolerance test
References in periodicals archive ?
Overnight fasting is also a common procedure in experiments of glucose metabolism or OGTT (e.
The glucose tolerance/insulin response test is based on a classic OGTT, with measurements made at baseline (fasting) and at multiple points after a glucose challenge.
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They divided patients into three separate groups: 338 who met GDM diagnosis by Carpenter-Coustan criteria, 281 who met GDM diagnosis by IADPSG criteria, and 7,771 who had a normal GDM screening or testing result (control group, defined as a normal 3-hour OGTT that would not be diagnosed with GDM by either IADPSG or Carpenter-Coustan criteria).
On the basis of the HAPO data, the panel suggested that a 75-g OGTT be performed and that GDM be diagnosed if any one of the values for fasting plasma glucose, 1-h glucose, or 2-h glucose equaled or exceeded the diagnostic threshold in Table 1.
The OGTT results of the patients were evaluated according to the American Diabetes Association (ADA) criteria for type 2 diabetes, impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) (8).
0mmol/l indicated an OGTT should be performed, 133 individuals met this criteria.
Basal insulin levels and glucose and insulin responses to OGTT were significantly higher in the patient group than in the control subjects (Table 1).
Although some LMC midwives do play a crucial role in encouraging women to have post-natal OGTT at six weeks post partum, my project entailed setting up systems to capture these high-risk women beyond the six-week period, when their care becomes a GP's responsibility.
Sonuc olarak tip 2 diyabet gelisme riski olan cocuklarda AKS yetinilmeyip mutlaka OGTT yapilmasi onerilmektedir (17).
Costs for screening with OGTT and genotyping were based on prices charged for services that implicitly include staff time, disposable supplies, and equipment depreciation.
Individuals treated with dapagliflozin plus glimepiride achieved significant reductions from baseline in the OGTT of -32.