is the gold standard for diagnosis of GDM.
Taking into account the parameters of insulin resistance (OGTT
values, HOMA-IR, and fasting insulin), fasting insulin was the best predictor of the non-responsiveness to clomiphene.
Commonly used diagnostic tests are fasting plasma glucose (FPG) and 75-gm oral glucose tolerance test (OGTT
The effect of mode of delivery (vaginal or caesarean section) on OGTT
results at 48 to 72 hours, and six weeks postpartum was also assessed.
Simple regression analyses were used to determine the influence of gender and Tanner stage on fasting insulin ([beta]=1.4; p=0.27 and [beta]= -1.2; p=0.14, respectively), HOMA-IR ([beta]=0.11; p=0.71 and [beta]= -0.4; p=0.03, respectively) and 2-hour insulin after an OGTT
([beta]=11; p=0.10 and [beta]=-5.8; p=0.17).
Of the 200 women, 31/200 (15.5%, 95% CI: 10.93-21.44) tested positive with the DIPSI criteria, and 26/200 (10.5%, 95% CI: 6.77-15.81) tested positive in the 100 gm OGTT
as per the CCC.
Only 61 (29.1%) practitioners were using an oral glucose tolerance test (OGTT
) for screening purposes; these included 50 gram OGTT
by 9 (4.29%), 75 gram OGTT
by 51 (24.29%) and 100 gram OGTT
by 1 (0.5%) respondent.
There are 2 sets of diagnostic criteria recommended for the 2-step process in the US; both are based on the "O'Sullivan criteria" for the 100-g glucose load, 3-h OGTT
derived by using 2 standard deviations above the mean for each of the 4 glucose values.
Since the new strategy using 75 g OGTT
as one-step screening is still controversial, and the prevalence of GDM varies among different racial groups, together with that it has never been tested in our obstetric population or those in most developing countries, where the people are biophysically different, we conducted this study to evaluate its effectiveness in our population.
The oral glucose tolerance test (OGTT
) and IP injection glucose tolerance test (IPIGTT) were performed at two and seven weeks after surgery, respectively.
The diagnosis of active disease was based on the clinical features of acromegaly, failure of GH suppression to below 1 [micro]g/l in response to a 75 g oral glucose tolerance test (OGTT
), plasma IGF-1 levels above the age-appropriate reference range, and radiological evidence of a pituitary tumor.
Oral Glucose Tolerance Test (OGTT
) and Insulin Release Test.