POU2F2

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POU2F2

A gene on chromosome 19q13.2 that encodes a transcription factor which regulates transcription in various tissues, in addition to activating immunoglobulin gene expression. It transcription transactivation by NR3C1, AR and PGR.
References in periodicals archive ?
The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin," Clinical Pharmacology and Therapeutics, vol.
creatinine, MDA, 8- in mice isoprostane, MRP2, and MRP4 [up arrow] OAT1, OAT3, OCT1, and OCT2 and survival rate of animals Xanthorrhizol 45 mg/kg, i.
19) Most cases also strongly express the B-cell transcription factors BOB1 and OCT2.
The large B cells are positive for pan-B-cell antigens including CD19, CD20, CD79a, PAX5, OCT2, and BOB1 with expression of CD45.
In most cases, HRS cells are characteristically positive for CD15 and CD30, with membranous staining and punctate accentuation in the Golgi area; they are also (weakly) reactive for PAX5 and either OCT2 or BOB1 (not both).
Immunophenotypically, the plasmablastic cells lack or only weakly express B-cell-associated antigens, such as CD20 and CD79a, but are positive for IRF4/MUM1, PRDM1/BLIMP1, and OCT2.
Combined Synopsis/Solicitation:Spectrails Traking OCT System- OCT Plus w OCT2