SLCO1C1

(redirected from OATP14)

SLCO1C1

A gene on chromosome 12p12.2 that encodes a protein which mediates Na+-independent high-affinity transport of organic anions (e.g., thyroxine and rT3) and lower-affinity transport of other substrates (e.g., triiodothyronine, 17-beta-glucuronosyl oestradiol, oestrone-3-sulfate and sulfobromophthalein). SLCO1C1 is thought to play a major role in regulating T4 flux in the brain.