OATP1 | definition of OATP1 by Medical dictionary
SLCO1A2 (redirected from OATP1)
Also found in: Acronyms
SLCO1A2 A gene on chromosome 12p12 that encodes a solute transporter that mediates the Na+-independent transport of organic anions such as sulfobromophthalein and conjugated (taurocholate) and unconjugated (cholate) bile acids. It is selectively inhibited by naringin in grapefruit juice.
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References in periodicals archive
In maternal liver, we detected Mrp2, Oatp1
a4, and Oatp1b2 expression (Figure 4A).
1292) evaluated the contribution of the transcription factor p53, as well as that of the hepatic uptake transporter for microcystin-LR (OATP1
B3), to the cellular response to microcystin-LR exposure.
2004), the marked difference between sexes in rats could be attributable to sex hormone regulation of the expression of certain organic anion transporters [OAT2 (Slc22a7), OAT3 (Slc22a8), and oatp1
(Slco1a1)] in the kidney (Kudo et al.