SLCO1A2

(redirected from OATP)
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SLCO1A2

A gene on chromosome 12p12 that encodes a solute transporter that mediates the Na+-independent transport of organic anions such as sulfobromophthalein and conjugated (taurocholate) and unconjugated (cholate) bile acids. It is selectively inhibited by naringin in grapefruit juice.
References in periodicals archive ?
Abbreviations ATP Adenosine Tri Phosphate BSEP Bile Salt Export Pump MDCKII Madin-Darby Canine Kidney Type II OAT Organic Anion Transporter OATP Organic Anion Transport Protein OCT Organic Cation Transporter MRP Multi Resistance Protein
Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver.
16-18) Additional studies have demonstrated that levofloxacin and other fluoroquinolones are substrates for both P-glycoprotein and OATP.
2002) reported that the OATP family expressed abundantly in the human placenta (e.