null allele

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null allele

A segment of DNA which is not known to encode a protein product.

null allele

a form of a gene whose product is either absent at the molecular level, or is present but has no measurable phenotypic function. For example, in a heterozygote with INCOMPLETE DOMINANCE one gene form is a ‘null allele’ and is inactive, while the other allele is unable to compensate for the null allele and so produces an intermediate phenotype.
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References in periodicals archive ?
Two loci (cmrDe2 and cmrDe9) showed significant deviations from H-W expectations, both with deficits of heterozygotes, possibly due to the presence of null alleles or the small sample size (Table 3).
Utility of five SSR markers for genetic diversity and paternity exclusion analysis in the Patagonian toothfish
Null alleles were detected in both wild and hatchery Mercenaria mercenaria.
Assessment of genetic diversity in wild and aquaculture stocks of Mercenaria mercenaria in Florida
2006) in study of costal cod (Gadus morpha), stated that several factor such as increasing homozigosit, genetic drift, selection, low sample size and null alleles is possibly cause of the Hardy-Weinberg disequilibrium.
Evaluation of genetic variation among endangered sea brown trout young fish for restocking to Caspian sea
The departure of allele frequencies from Hardy-Weinberg expectations at all microsatellite loci used in this study indicated the presence of null alleles (Jones and Arden, 2003).
Patterns of male reproductive success in Crepidula fornicata provide new insight for sex allocation and optimal sex change
Analysis with MICRO-CHECKER indicated the possibility of null alleles at one microsatellite (Lca 20) where the probability of deviation from Hardy-Weinberg equilibrium expectations was significant (P=0.009) before Bonferroni correction.
Microsatellite multiplex panels for genetic studies of gray snapper (Lutjanus griseus) and lane snapper (Lutjanus synogris)
We also selected the more rare SNPs M46V, G99E, K139E, and I391N, described as phenotypic null alleles in Caucasians, and the R140Q SNP that strongly affects enzyme activity (21).
MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms
Lines were developed from matings between Asian and North American sources of the Wx null alleles. After the last cross in each pedigree, the brush end of [F.sub.2] plants was stained with a dilute solution of [I.sub.2]KI and the germ end was saved for planting.
Registration of nineteen waxy spring wheats
Null alleles at microsatellite loci are a general complication for parentage assessments in nature (Callen et al.
Polygynandry in the dusky pipefish Syngnathus floridae revealed by microsatellite DNA markers
The frequency of null alleles varied from -0.0548 to 0.0563 and none of these loci showed evidence of null alleles.
Short Communication - Isolation and Characterization of Microsatellite Markers for the Sable, Martes zibellina (Mammalia: Mustelidae)
Null alleles were present in all locations for loci Mgu1, Mgu3, MT203, Mg15, Mg56, and MIT02 and in some locations for loci MT282 and Med737 but not detected in any location for locus MGE005.
Heterologous microsatellite-based genetic diversity in blue mussel (Mytilus chilensis) and differentiation among localities in southern Chile/Diversidad genetica del mejillon (Mytilus chilensis) y diferenciacion entre localidades del sur de Chile usando marcadores microsatelites heterologos
In this case, the nature of the deviations is suggestive of null alleles, as indicated by the MICRO-CHECKER analysis.
Genetic analysis of cuttlefish Sepia pharaonis (Ehrenberg, 1831) populations in Persian gulf with microsatellite markers
Null alleles were detected at loci D11 and K37 in the Tasik Bera and Endau River populations.
Genetic variability and estimation of effective population sizes of the natural populations of green arowana, Scleropages formosus in Peninsular Malaysia

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