Schwebke et al (41) compared Amsel's clinical criteria with Nugent's criteria and showed that the Nugent criteria
had a higher sensitivity of 89% and Amsel's criteria had a higher specificity of 94%.
The smears were then assessed according to Nugent criteria
Their symptoms were assessed clinically by Amsel criteria; bacterial vaginosis was confirmed with Gram stain of vaginal fluid and Nugent criteria
. The overall prevalence of BV was 29%, which is higher than that usually seen at clinics in the United States, Dr.
Vaginal flora was evaluated by Gram stain according to Nugent criteria
, and BV was defined as a Nugent score > 7, with severe BV having a Nugent score > 9 and vaginal pH > 5.
Using the Nugent criteria
, women who were diagnosed with BV received a 6-day course of intravaginal clindamycin 2% cream.
In all, 96 women without BV by Nugent criteria
were enrolled into a prospective, longitudinal study.
Additionally, the sample had the largest group of sexually inexperienced women ever evaluated for bacterial vaginosis with the Nugent criteria
. Finally, it was large enough to allow comparisons across racial and ethnic groups.
The diagnostic criteria in the present study were gram staining and Nugent criteria.
The second most commonly used diagnostic test involves a Gram stain of vaginal discharge and applying Nugent criteria. The Nugent criterion (15) is the test most often used in epidemiologic studies in large scale, this method has several advantages that include 1) creating a permanent record that can be subsequently reviewed to confirm the diagnosis of BV and assess the reliability of the reading, 2) reporting intermediate stages of BV, which is particularly useful and 3) quantifying the amount of the three individual organisms, enabling assessment of the organism-specific risk of disease.