nude mouse

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Related to Nude mice: SCID mice

mouse

 [mows]
a small rodent, various species of which are used in laboratory experiments.
1. a small loose body.
2. a computer pointing device.
joint mouse a movable fragment of synovial membrane, cartilage, or other body within a joint; usually associated with degenerative osteoarthritis and osteochondritis dissecans.
knockout mouse a mouse that has had a specific gene artificially deleted from its genome.
nude mouse a mouse homozygous for the nu gene; these mice are hairless, lack a thymus, and thus lack T lymphocytes.
peritoneal mouse a free body in the peritoneal cavity, probably a small detached mass or omentum, sometimes visible radiographically.
SCID mouse (severe combined immunodeficiency) a strain of mice lacking in T and B lymphocytes and immunoglobulins, either from inbreeding with an autosomal recessive trait or from genetic engineering, used as a model for studies of the immune system.

nude mouse

a hairless mutant mouse with thymic hypoplasia, lacking T cells.
A mutant strain of lab mouse that is hairless, thymusless due to congenital thymic aplasia, and T cell-less.

nude mouse

inbred strain of laboratory mouse which is hairless and has no thymic tissue. Because it has no source of T lymphocytes, it suffers from a defect in cell-mediated immunity and is highly susceptible to infections. This trait is utilized for immunological studies. Called also athymic mouse.
References in periodicals archive ?
Courey evaluated the histologic characteristics of homologous collagen compounds injected into the quadriceps muscles of nude mice.
low]HBECs reversed their transformed phenotypes, as evidenced by inhibition of colony formation in soft agar and prevention of xenograft tumor formation in nude mice (Wang et al.
Intraperitoneal adenovirus-mediated suicide gene therapy in combination with either topotecan or paclitaxel in nude mice with human ovarian cancer.
Epidermal growth factor receptor blockade by antibody IMC-C225 inhibits growth of a human pancreatic carcinoma xenograft in nude mice.
EBV DNA was detected in the plasma of all nude mice inoculated with EBV-positive cells (C666 cell line and Xeno-2117).
Using nude mice, "we've put it in the middle of a cancer," he says, "and over the next day or two it diffused throughout the tumor.
This class of isoquinolinamine compounds significantly inhibited the growth of paclitaxel (Taxol([R])) resistant HCT-15 human colorectal cancer cells and tumor growth in an in vivo model of nude mice injected with paclitaxel-resistant HCT-15 human colorectal cancer cells.
A study entitled "Anticancer effects of amooranin in human colon carcinoma cell line in vitro and in nude mice xenografts," appeared in the International Journal of Cancer (2006), concluded methyl amooranin may be advantageous for the inhibition of tumor growth.
Athymie nude mice Hep3B xenograft model further demonstrated that this 2-Formyl-8-hydroxy-quinolinium chloride could execute strong anti-tumour activity with the identification of extensive necrotic feature from the tumour xenograft and limited adverse toxicological effect.
Our needs are defined by the following four points 1 - Control of conventional zones, mice and rats, as recommended FELASA2 - Control the mouse zones SOPF and SPF as recommended FELASA3 - Control of nude mice as recommended FELASA4 - Test spot health checks(See specifications)
We investigated the in vivo growth inhibitory effects of apigenin on androgen-sensitive human prostate carcinoma 22Rv1 tumor xenograft subcutaneously implanted in athymic male nude mice.