nucleosome

(redirected from Nucleosomes)
Also found in: Dictionary, Encyclopedia.

nucleosome

 [noo´kle-o-sōm″]
any of the complexes of histone and DNA in eukaryotic cells, seen under the electron microscope as beadlike bodies on a string of DNA.

nu·cle·o·some

(nū'klē-ō-sōm'),
A localized aggregation of histone and DNA that is evident when chromatin is in the uncondensed stage.
Synonym(s): nu body
[nucleo- + G. sōma, body]

nucleosome

/nu·cleo·some/ (-sōm) any of the complexes of histone and DNA in eukaryotic cells, seen under the electron microscope as beadlike bodies on a string of DNA.

nucleosome

(no͞o′klē-ə-sōm′, nyo͞o′-)
n.
Any of the repeating subunits of chromatin found in eukaryotes, consisting of a DNA chain coiled around a core of histones.

nu′cle·o·som′al (-sō′məl) adj.

nucleosome

[no̅o̅′klē·əsōm′]
Etymology: L, nucleus + Gk, soma, body
any one of the repeating DNA-histone complexes that appear as beadlike structures at distinct intervals along a chromosome.

nucleosome

A nucleic acid and protein complex, which is the basic structural unit of chromatin, composed of a segment of DNA wrapped around a core of histone molecules.

nu·cle·o·some

(nū'klē-ō-sōm)
A localized aggregation of histone and DNA that is evident when chromatin is in the uncondensed stage.
[nucleo- + G. sōma, body]

nucleosome

The structural subunit of CHROMATIN consisting of about 200 BASE PAIRS and a barrel-shaped core of eight histone protein molecules (an octamer).

nucleosome

the basic structural unit of the eukaryote chromosome, being composed of four pairs of HISTONE proteins (H2A, H2B, H3 and H4) that are combined to form an octomer around which is wrapped about 150 nucleotide pairs of DNA.

nucleosome

any of the complexes of histone and DNA in eukaryotic cells, seen under the electron microscope as beadlike bodies on a string of DNA.
References in periodicals archive ?
The nucleosomes and the higher order chromatin structures must be modified to facilitate the accessibility of these factors to hormone response sequences.
Additionally, chromatin structure, and thus gene expression, is influenced by the specific combination of histone variants in a nucleosome, the spacing between nucleosomes (i.
Nucleosomes are considered to be the basic element of chromatin.
Chromatin is structured within the cell nucleus in units called nucleosomes, in which DNA is packaged within the cell.
First there is the helix; then the helix is twined around nucleosomes, structures made of eight histone proteins involved in controlling whether or not the DNA is transcribed.
This may be explained by the fact that not only pathogen-associated molecular patterns but also endogenous alarmins, such as high mobility group box proteins, heat shock proteins or nucleosomes, contain hydrophobic motifs and are recognised by toll-like receptors (27-29).
Huge complex proteins called nucleosomes facilitate this DNA compaction so that eventually the DNA is coiled in an ordered manner to form chromosomes.
The internal breakage hot spot showed prominent H3 binding consistent with the presence of nucleosomes.
11,14) This results in the persistence of autoreactive T cells and allows the release of structurally abnormal nucleosomes, as well as excess intraglomerular generation of nucleosomes that contribute to glomerular immune deposits.
Nucleosomes and other proteins bundle long strands of DNA into packages small enough to be encased in a cell's nucleus.
These cell-free nucleosomes can be analysed for histone code modifications.