Nucleic Acid Vaccine | definition of Nucleic Acid Vaccine by Medical dictionary
DNA vaccine (redirected from Nucleic Acid Vaccine)
Also found in: Encyclopedia
a vaccine employing naked DNA from an organism to which immunity is intended to be conveyed; use remains in experimental stages..A technique for protecting an organism against disease by injecting it with genetically engineered DNA to produce an immune response. This experimental vaccine carries a gene that encodes a protein responsible for an immune reaction against the pathogen of interest, which may be directly injected IM
Molecular medicine A vaccine in which a simple injection of a gene evokes the desired immune response to the protein encoded by the gene
Potential DNA vaccines Influenza, herpes, malaria, HIV, HPV, TB, chlamydia, hepatitis
DNA vaccine an experimental VACCINE technology in which one or more genes encoding specific ANTIGENS are directly injected into the body, with a view to antigen production and stimulation of the IMMUNE RESPONSE. Such vaccines include several HIV genes. The technology would be useful for the production of inexpensive and heat-stable vaccines.
References in periodicals archive
"With the nucleic acid vaccine, DNA is very easy to grow in culture.
The advantages of these so called nucleic acid vaccines, versus the typical vaccine, are numerous.
Factors like insertion of large segments of DNA in the nucleic acid vaccines
and their expression systems are difficult.
The application of nucleic acid vaccines
against parasitic diseases has recently been reported.