5] M), we judged the PBDEs and their metabolites to be positive for agonistic or antagonistic activity against that nuclear hormone receptor
The new SwitchGear pathway sets utilize experimentally-validated luciferase reporter vectors to accurately quantify human promoter activity from complete sets of genes associated with inflammation, cholesterol biosynthesis, oncology, vascular biology, nuclear hormone receptor
signaling, and many other important biological pathways.
Nasdaq:EXEL) today announced that it has signed an extension of the company's research collaboration agreement with Bristol-Myers Squibb Company (NYSE:BMY) to discover novel therapies targeted against the Liver X Receptor (LXR), a nuclear hormone receptor
implicated in a variety of cardiovascular and metabolic disorders.
The research in Chapter 7 describes gene expression changes in both in vivo and in vitro rat liver cells treated with nuclear hormone receptor
Glitazones appear to act primarily through the activation of the nuclear hormone receptor
Binding of a peroxisome proliferator (ligand) to PPAR[Alpha] activates this nuclear hormone receptor
is a biopharmaceutical company dedicated to the discovery, development, and commercialization of novel, selective, small molecule nuclear hormone receptor
modulators targeting hormone pathways to address a myriad of unmet medical needs in men and women.
New screening methods for chemicals with hormonal activities using interaction of nuclear hormone receptor
Glitazones appear to act primarily through the activation of nuclear hormone receptor
The Locus approach was used to target nuclear hormone receptor
antagonists called Selective Estrogen Receptor Covalent Antagonists (SERCAs) that inactivate the estrogen receptor by targeting a cysteine that is not present in other nuclear hormone receptors
Specific and overlapping functions of the nuclear hormone receptors
CAR and PXR in xenobiotic response.