noradrenaline reuptake inhibitor


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noradrenaline reuptake inhibitor

One of a class of drugs that function by increasing the available amount of the neurotransmitter NORADRENALINE at synapses. This is achieved by interfering with the normal physiological reuptake mechanism that brings about the removal of noradrenaline from the synaptic gap. Selective noradrenaline reuptake inhibitors can have a useful antidepressive effect. They include AMITRIPTYLINE, CLOMIPRAMINE, DOXEPIN, IMIPRAMINE, AMOXAPINE, MAPROTILINE and NORTRIPTYLINE.
References in periodicals archive ?
X Serotonin Noradrenaline reuptake inhibitors - Both the EFNS and AAN guidelines support the use of duloxetine (dose 60-120 mg/day) and venlafaxine (dose 75-225mg/day).21 Common side effects include nausea, somnolence, dry mouth, and constipation.
Tricyclic antidepressants (TCA), monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs) and serotonin noradrenaline reuptake inhibitors (SNRIs) all increase the concentration of monoamine neurotransmitters in the synaptic cleft, with varying degrees of specificity.
Randomized placebo-controlled trials with tricyclic and tetracyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and monoamine oxidase inhibitors (MAOIs) were analyzed.
4 SNRIS (serotonin and noradrenaline reuptake inhibitors) work in a similar way to SSRIs with side effects of nausea, headaches, dizziness and sweating.
David Healey, director of the North Wales Department of Psychological Medicine noted the link between the new antidepressants-Selective Serotonin Re-uptake Inhibitors or SSRI'S and Serotonin Noradrenaline Reuptake Inhibitors or SNRI'S--and an increased risk of suicide and violent behaviour in teenagers or children, who were prescribed the drugs.
Reboxetine is the first in a new class of drugs, called selective noradrenaline reuptake inhibitors. These drugs may treat patients more reliably than some selective serotonin reuptake inhibitors without subjecting them to the side effects associated with tricycic antidepressants, reported Dr.
There are four types of anti-depressants: Tricyclics, such as Tryptizol (the cheapest, as you'll see from our guide on the right) and Anafranil; Mono amine oxidase inhibitors (MAOIs), such as Nardil and Parnate; Selective Serotonin Reuptake Inhibitors (SSRIs) such as Prozac and Lustral (the most expensive); and Serotonin and Noradrenaline Reuptake Inhibitors (SNRIs), such as Efexor.
** Serotonin- noradrenaline reuptake inhibitors. *** Noradrenergic and specific serotonergic antidepressants.